4-(4-氯苯基)-2-甲砜基嘧啶合成路线 (共 2 条)
反应条件
oxone in water; acetone
参考文献
Satoh, Yoshitaka; Bhagwat, Shripad S.
Patent: US2004/106634 A1, 2004 ;
US 20040106634 A1
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; ethanol; toluene / 18 h / 90 °C / |Sealed tube; |Inert atmosphere
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C
View Scheme
参考文献
ACTELION PHARMACEUTICALS LTD; AISSAOUI, Hamed; BOSS, Christoph; CIANA, Claire-Lise; SIEGRIST, Romain
Patent: WO2014/72903 A1, 2014 ;