4-(吡咯烷-3-基)哌嗪-1-羧酸苄酯合成路线 （共 2 条）
反应条件
1: With titanium(IV) isopropylate
1 h;
2: With sodium cyanoborohydride in ethanol
T=20°C;
3: With water; sodium hydrogencarbonate; trifluoroacetic acid
more than 3 stages;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2006/74925 A1, 2006 ;
Location in patent: Page/Page column 95 ;
WO 2006/074925 A1
反应条件
sodium cyanoborohydride; trifluoroacetic acid in ethanol; water; ethyl acetate
参考文献
Bilodeau, Mark T.; Hartman, George D.; Hoffman JR., Jacob M.; Sisko, John T.; Manley, Peter J.; Smith, Anthony M.; Tucker, Thomas J.; Lumma JR., William C.; Rodman, Leonard
Patent: US2002/137755 A1, 2002 ;
US 20020137755 A1
