1: 2,6-dimethylpyridine / dichloromethane / 0.25 h / -78 °C / |Inert atmosphere 2: (N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)CuOtBu; 1,1,3,3-tetramethyldisiloxane; cesium fluoride / 1,4-dioxane / 4 h / 25 °C / |Glovebox; |Inert atmosphere View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4267587', constants.ctx, '0')">potassium carbonate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605365', constants.ctx, '0')">N,N-dimethyl-formamide</a> <br />18&nbsp;h;&nbsp;&nbsp;Reflux;&nbsp;<br /> &nbsp;

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '1904544', constants.ctx, '0')">4-hydroxyiodobenzene</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342937', constants.ctx, '0')">potassium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a> <br />1&nbsp;h;&nbsp;&nbsp;Heating;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '1697307', constants.ctx, '0')">6-chlorohexyl alcohol</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a> <br />24&nbsp;h;&nbsp;&nbsp;Heating;&nbsp;<br /> &nbsp;