2-(4-甲基苯基)-1-丙醇合成路线 (共 24 条)
反应条件
lithium aluminium tetrahydride; meta-chloroperoxybenzoic acid
2.) ether, 30 min, reflux; study of the regioselectivity of autoxidation by reduction of the corresponding oxidation-mixture; MechanismProduct distribution;
参考文献
Pritzkow, Wilhelm; Thomas, Gerda; Willecke, Lothar
Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 847 - 851
反应条件
metabolism in rabbits;
参考文献
Ishida; Asakawa; Takemoto; Aratani
Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 4 p. 406 - 415
反应条件
the enantioselective metabolism of p-cymene in rabbits;
参考文献
Matsumoto; Ishida; Yoshida; Terao; Takeda; Asakawa
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 7 p. 1721 - 1726
反应条件
1: triphenylphosphorane, bromine / 2.) pyridine, room temperature, 1 h
2: 1.) butyllithium / 1.) -65 to -30 deg C, 2.) -70 deg C
3: 57 percent / HgO/HgCl2 / diethyl ether
View Scheme
参考文献
Bokel, H. H.; Hoppmann, A.; Weyerstahl, P.
Tetrahedron, 1980 , vol. 36, # 5 p. 651 - 654