1: 4-aminophthalimide With sodium hydride in N,N-dimethyl-formamide 0.5 h; 2: ethylene dibromide in N,N-dimethyl-formamide T=20°C; 24 h;

palladium on activated charcoal; ammonium formate in tetrahydrofuran T=20°C; 12 h;

1.1: nitric acid; sulfuric acid / 16 h / 5 - 20 °C 2.1: potassium hydroxide / methanol; ethanol / 3 h / 20 °C 2.2: 1 h / |Reflux 3.1: palladium on activated charcoal; ammonium formate / tetrahydrofuran / 12 h / 20 °C View Scheme

1.1: potassium hydroxide / methanol; ethanol / 3 h / 20 °C 1.2: 1 h / |Reflux 2.1: palladium on activated charcoal; ammonium formate / tetrahydrofuran / 12 h / 20 °C View Scheme