1.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 4 h / 20 °C 2.1: sodium hydride / tetrahydrofuran; hexane; mineral oil / 0.17 h / 0 °C 2.2: 0 - 20 °C 3.1: pyridine / dichloromethane / 2 h / 0 °C 4.1: diisobutylaluminium hydride / toluene / 0.5 h / -78 °C 5.1: dichloromethane / 1 h / 0 °C 6.1: sodium carbonate / tert-butyl benzene / 24 h / 170 °C 7.1: diisobutylaluminium hydride / toluene / 1 h / -78 °C 8.1: potassium carbonate / tetrahydrofuran; water / 3 h / 0 °C 9.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C 10.1: scandium tris(trifluoromethanesulfonate) / dichloromethane; water / 20 - 40 °C 11.1: Jone's reagent / water; acetone / 0 - 20 °C 12.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 13.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 14.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 15.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 16.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 16.2: 0.33 h / -78 °C 16.3: 6 h / -78 °C 17.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 18.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 19.1: BOPCl / dichloromethane / 2 h / 20 °C 20.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme

1.1: sodium hydride / tetrahydrofuran; hexane; mineral oil / 0.17 h / 0 °C 1.2: 0 - 20 °C 2.1: pyridine / dichloromethane / 2 h / 0 °C 3.1: diisobutylaluminium hydride / toluene / 0.5 h / -78 °C 4.1: dichloromethane / 1 h / 0 °C 5.1: sodium carbonate / tert-butyl benzene / 24 h / 170 °C 6.1: diisobutylaluminium hydride / toluene / 1 h / -78 °C 7.1: potassium carbonate / tetrahydrofuran; water / 3 h / 0 °C 8.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C 9.1: scandium tris(trifluoromethanesulfonate) / dichloromethane; water / 20 - 40 °C 10.1: Jone's reagent / water; acetone / 0 - 20 °C 11.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 12.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 13.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 14.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 15.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 15.2: 0.33 h / -78 °C 15.3: 6 h / -78 °C 16.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 17.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 18.1: BOPCl / dichloromethane / 2 h / 20 °C 19.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme

1.1: diisobutylaluminium hydride / toluene / 1 h / -78 °C 2.1: potassium carbonate / tetrahydrofuran; water / 3 h / 0 °C 3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C 4.1: scandium tris(trifluoromethanesulfonate) / dichloromethane; water / 20 - 40 °C 5.1: Jone's reagent / water; acetone / 0 - 20 °C 6.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 7.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 8.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 9.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 10.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 10.2: 0.33 h / -78 °C 10.3: 6 h / -78 °C 11.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 12.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 13.1: BOPCl / dichloromethane / 2 h / 20 °C 14.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C 2.1: scandium tris(trifluoromethanesulfonate) / dichloromethane; water / 20 - 40 °C 3.1: Jone's reagent / water; acetone / 0 - 20 °C 4.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 5.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 6.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 7.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 8.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 8.2: 0.33 h / -78 °C 8.3: 6 h / -78 °C 9.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 10.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 11.1: BOPCl / dichloromethane / 2 h / 20 °C 12.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C 2.1: water; acetic acid / 48 h / 20 °C 3.1: 4-(N,N-dimethlyamino)pyridine / pyridine / 24 h / 20 °C 4.1: acetic anhydride; dimethyl sulfoxide / 2 h / 50 °C 5.1: toluene / 4 h / -40 °C 6.1: magnesium / methanol / 2 h / 20 °C 7.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 4 h / 20 °C 8.1: sodium hydride / tetrahydrofuran; hexane; mineral oil / 0.17 h / 0 °C 8.2: 0 - 20 °C 9.1: pyridine / dichloromethane / 2 h / 0 °C 10.1: diisobutylaluminium hydride / toluene / 0.5 h / -78 °C 11.1: dichloromethane / 1 h / 0 °C 12.1: sodium carbonate / tert-butyl benzene / 24 h / 170 °C 13.1: diisobutylaluminium hydride / toluene / 1 h / -78 °C 14.1: potassium carbonate / tetrahydrofuran; water / 3 h / 0 °C 15.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C 16.1: scandium tris(trifluoromethanesulfonate) / dichloromethane; water / 20 - 40 °C 17.1: Jone's reagent / water; acetone / 0 - 20 °C 18.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 19.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 20.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 21.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 22.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 22.2: 0.33 h / -78 °C 22.3: 6 h / -78 °C 23.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 24.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 25.1: BOPCl / dichloromethane / 2 h / 20 °C 26.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme

1.1: water; acetic acid / 48 h / 20 °C 2.1: 4-(N,N-dimethlyamino)pyridine / pyridine / 24 h / 20 °C 3.1: acetic anhydride; dimethyl sulfoxide / 2 h / 50 °C 4.1: toluene / 4 h / -40 °C 5.1: magnesium / methanol / 2 h / 20 °C 6.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 4 h / 20 °C 7.1: sodium hydride / tetrahydrofuran; hexane; mineral oil / 0.17 h / 0 °C 7.2: 0 - 20 °C 8.1: pyridine / dichloromethane / 2 h / 0 °C 9.1: diisobutylaluminium hydride / toluene / 0.5 h / -78 °C 10.1: dichloromethane / 1 h / 0 °C 11.1: sodium carbonate / tert-butyl benzene / 24 h / 170 °C 12.1: diisobutylaluminium hydride / toluene / 1 h / -78 °C 13.1: potassium carbonate / tetrahydrofuran; water / 3 h / 0 °C 14.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C 15.1: scandium tris(trifluoromethanesulfonate) / dichloromethane; water / 20 - 40 °C 16.1: Jone's reagent / water; acetone / 0 - 20 °C 17.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 18.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 19.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 20.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 21.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 21.2: 0.33 h / -78 °C 21.3: 6 h / -78 °C 22.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 23.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 24.1: BOPCl / dichloromethane / 2 h / 20 °C 25.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme

1.1: 4-(N,N-dimethlyamino)pyridine / pyridine / 24 h / 20 °C 2.1: acetic anhydride; dimethyl sulfoxide / 2 h / 50 °C 3.1: toluene / 4 h / -40 °C 4.1: magnesium / methanol / 2 h / 20 °C 5.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 4 h / 20 °C 6.1: sodium hydride / tetrahydrofuran; hexane; mineral oil / 0.17 h / 0 °C 6.2: 0 - 20 °C 7.1: pyridine / dichloromethane / 2 h / 0 °C 8.1: diisobutylaluminium hydride / toluene / 0.5 h / -78 °C 9.1: dichloromethane / 1 h / 0 °C 10.1: sodium carbonate / tert-butyl benzene / 24 h / 170 °C 11.1: diisobutylaluminium hydride / toluene / 1 h / -78 °C 12.1: potassium carbonate / tetrahydrofuran; water / 3 h / 0 °C 13.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C 14.1: scandium tris(trifluoromethanesulfonate) / dichloromethane; water / 20 - 40 °C 15.1: Jone's reagent / water; acetone / 0 - 20 °C 16.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 17.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 18.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 19.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 20.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 20.2: 0.33 h / -78 °C 20.3: 6 h / -78 °C 21.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 22.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 23.1: BOPCl / dichloromethane / 2 h / 20 °C 24.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme

1.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 20 °C 2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C 3.1: Jone's reagent / water; acetone / 0 - 20 °C 4.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 5.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 6.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 7.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 8.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 8.2: 0.33 h / -78 °C 8.3: 6 h / -78 °C 9.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 10.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 11.1: BOPCl / dichloromethane / 2 h / 20 °C 12.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme

1.1: Jone's reagent / water; acetone / 0 - 20 °C 2.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 3.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 4.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 5.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 6.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 6.2: 0.33 h / -78 °C 6.3: 6 h / -78 °C 7.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 8.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 9.1: BOPCl / dichloromethane / 2 h / 20 °C 10.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme

1.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C 2.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 3.1: 2,6-dimethylpyridine / N,N-dimethyl-formamide / 20 - 60 °C 4.1: pyridine; sodium periodate; osmium(VIII) oxide / water; tert-butyl alcohol / 20 - 50 °C 5.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C 5.2: 0.33 h / -78 °C 5.3: 6 h / -78 °C 6.1: boron trichloride / n-heptane; dichloromethane / 0.67 h / 0 °C 7.1: water / n-heptane; dichloromethane / 0.33 h / 0 °C 8.1: BOPCl / dichloromethane / 2 h / 20 °C 9.1: dichlorotriphenylphosphorane / pyridine; acetonitrile / 3 h / 20 °C View Scheme