4-(4-氨基苯基)吗啉-3-酮合成路线 （共 14 条）
反应条件
in ethanol; water 27 h; Heating;
参考文献
Roehrig, Susanne; Straub, Alexander; Pohlmann, Jens; Lampe, Thomas; Pernerstorfer, Josef; Schlemmer, Karl-Heinz; Reinemer, Peter; Perzborn, Elisabeth
Journal of Medicinal Chemistry, 2005 , vol. 48, # 19 p. 5900 - 5908
参考文献
BAYER HEALTHCARE AG
Patent: US2010/160301 A1, 2010 ;
US 20100160301 A1
反应条件
1: methanol / 16 h / Reflux 2: N,N-dimethyl-formamide / 5 h View Scheme
参考文献
APOTEX PHARMACHEM INC.; BODHURI, Prabhudas; WEERATUNGA, Gamini
Patent: WO2012/51692 A1, 2012 ;
反应条件
1.1: ethanol / 9 h / 80 °C 2.1: tetrahydrofuran / 4 h / |Reflux 3.1: methylamine / ethanol; water / 2 h / 65 °C 3.2: 65 °C / pH 2.7 View Scheme
参考文献
SYMED LABS LIMITED; MOHAN RAO, Dodda; KRISHNA REDDY, Pingili; VENKAT REDDY, Buthukuri
Patent: WO2013/46211 A1, 2013 ;
