2,3-二氢-1,4-苯并二噁英-2-酮合成路线 （共 14 条）
反应条件
copper oxide-chromium oxide T=250°C; P=73550.8 - 147102 Torr; Hydrogenolyse;
参考文献
McClellan; Connor
Journal of the American Chemical Society, 1941 , vol. 63, p. 484,486
反应条件
T=200°C; P=73550.8 - 147102 Torr; Hydrogenation;
参考文献
McClellan; Connor
Journal of the American Chemical Society, 1941 , vol. 63, p. 484,486
反应条件
1: H2O 2: (i) aq. NaOH, (ii) /BRN= 605267/ View Scheme
参考文献
Imp.Chem.Ind.
Patent: DE2126169 , 1971 ;
Chem.Abstr., 1972 , vol. 76, # 72289
反应条件
ammonia in water Ring cleavage; amidation; 2 h;
参考文献
Anisimova; Turchin; Golovanova; Vinogradova; Yuzhakov; Mashkovskii; Pleshkova; Sheinker
Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 5 p. 224 - 228
参考文献
Imperial Chemical Industries Limited
Patent: US4059622 A1, 1977 ;
US 4059622 A
参考文献
Imp.Chem.Ind.
Patent: DE2126169 , 1971 ;
Chem.Abstr., 1972 , vol. 76, # 72289
反应条件
TEA in dichloromethane
4 h; Heating;
参考文献
Gandolfi, Carmelo A.; Domenico, Roberto Di; Spinelli, Silvano; Gallico, Licia; Fiocchi, Luigi; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 3 p. 508 - 525
参考文献
Ghosh
Journal of the Chemical Society, 1915 , vol. 107, p. 1595
反应条件
toluene-4-sulfonic acid in benzene
3 h; Heating;
参考文献
Sampson, Peter; Crook, Michelle; Piorko, Adam
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 4 p. 1011 - 1016
反应条件
1: EtONa / ethanol / 16 h / Heating
2: 21 percent / conc. HCl / 1 h / Heating
3: 18 percent / PTSA / benzene / 3 h / Heating
View Scheme
参考文献
Sampson, Peter; Crook, Michelle; Piorko, Adam
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 4 p. 1011 - 1016
