1,3-二氧戊环-2-丙腈合成路线 （共 11 条）
反应条件
in hexane; dimethyl sulfoxide; ethyl acetate
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US6319946 B1, 2001 ;
US 6319946 B1
反应条件
potassium iodide in N,N-dimethyl-formamide
T=100 - 120°C; 3 h;
参考文献
Iwamoto, Minoru; Takagi, Yoshikazu; Kogami, Kunio; Hayashi, Kazuo
Agricultural and Biological Chemistry, 1983 , vol. 47, # 1 p. 115 - 116
反应条件
N-benzyl-N,N,N-trimethyl-ammonium chloride in water
T=90°C; 4 h;
参考文献
Shimizu; Ishikawa; Komoda; Nakajima
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 3 p. 909 - 914
反应条件
toluene-4-sulfonic acid in dichloromethane
2 h; Heating;
参考文献
Shrestha-Dawadi, Prativa Bade; Lugtenburg, Johan
European Journal of Organic Chemistry, 2003 , # 23 p. 4654 - 4663
反应条件
in N-methyl-acetamide; dichloromethane; water
参考文献
Gensia, Inc.
Patent: US5775329 A1, 1998 ;
反应条件
in water; ethylene glycol
T=100°C; 3 h;
参考文献
Nakao, Yoshiaki; Yada, Akira; Hiyama, Tamejiro
Journal of the American Chemical Society, 2010 , vol. 132, # 29 p. 10024 - 10026
反应条件
in dimethyl sulfoxide
参考文献
Mendez, Jose Manuel; Flores, Blas; Leon, Fernando; Martinez, Maria Eugenia; Vazquez, Alfredo; Garcia, Gustavo Alberto; Salmon, Manuel
Tetrahedron Letters, 1996 , vol. 37, # 24 p. 4099 - 4102
反应条件
carbon monoxide; hydrogen; ethylene glycol
T=175°C; P=294203 Torr; Reagens 4: Hydrochinon; Kobalt-Thorium-Kieselgur-Katalysator;
参考文献
Du Pont de Nemours and Co.
Patent: US2506571 , 1948 ;
反应条件
tetrabutylammonium decatungstate in acetonitrile
UV-irradiation;
参考文献
Dondi, Daniele; Fagnoni, Maurizio; Albini, Angelo
Chemistry - A European Journal, 2006 , vol. 12, # 15 p. 4153 - 4163
反应条件
di-tert-butyl peroxide
参考文献
Safiev, O. G.; Kruglov, D. E.; Popov, Yu. N.; Zlot-skii, S. S.; Rakhmankulov, D. L.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, # 5 p. 997 - 1000
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 5 p. 1096 - 1100
