2-氨基-3-甲基苯甲酸合成路线 （共 84 条）
反应条件
1: 2 h / 170 °C
2: POCl3, dimethylaniline / toluene / 4 h / Heating
View Scheme
参考文献
Luo, Hui; Liu, Jiaju; Jin, Linhong; Hu, Deyu; Chen, Zhen; Yang, Song; Wu, Jian; Song, Baoan
European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 662 - 669
反应条件
1: potassium carbonate; nitrobenzene; copper / 185 °C
2: phosphoryl chloride / 120 °C
View Scheme
参考文献
Albert; Gledhill
Journal of the Society of Chemical Industry, London, 1945 , vol. 64, p. 169,170
参考文献
Ghosh,K.; Bhattacharya,A.J.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1977 , vol. 15, p. 32 - 35
反应条件
1: aq. AcOH / 2 h
2: POCl3, N,N-dimethylaniline / 5 h / Heating
View Scheme
参考文献
Smits, Rogier A.; Lim, Herman D.; Van Der Meer, Tiffany; Kuhne, Sebastiaan; Bessembinder, Karin; Zuiderveld, Obbe P.; Wijtmans, Maikel; De Esch, Iwan J.P.; Leurs, Rob
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 461 - 467
