2-氨基-6-甲基苯甲酸合成路线

参考文献

Comess, Kenneth M.; Erickson, Scott A.; Henkin, Jack; Kalvin, Douglas M.; Kawai, Megumi; Kim, Ki H.; BaMaung, Nwe Y.; Park, Chang Hoon; Sheppard, George S.; Vasudevan, Anil; Wang, Jieyi; Barnes, David M.; Fidanze, Steve D.; Kolaczkowski, Lawrence; Mantei, Robert A.; Park, David C.; Sanders, William J.; Tedrow, Jason S.; Wang, Gary T.
Patent: US2004/157836 A1, 2004 ;

24424-99-5二碳酸二叔丁酯+

4389-50-82-氨基-6-甲基苯甲酸+

77-92-9柠檬酸

269391-47-1

参考文献

Altmann, Karl-Heinz; Bold, Guido; Furet, Pascal; Manley, Paul William; Wood, Jeanette Marjorie; Ferrari, Stefano; Hofmann, Francesco; Mestan, Jurgen; Huth, Andreas; Kruger, Martin; Seidelmann, Dieter; Menrad, Andreas; Haberey, Martin; Thierauch, Karl-Heinz
Patent: US2002/19414 A1, 2002 ;

4389-50-82-氨基-6-甲基苯甲酸

99548-56-82-溴-6-甲基苯甲酸甲酯

参考文献

Abbott Laboratories; Abbott GmbH and Co. KG
Patent: US2013/5705 A1, 2013 ;
US 20130005705 A1

4389-50-82-氨基-6-甲基苯甲酸

79383-44-12-甲氧基-6-甲基苯甲酸甲酯

参考文献

Baur, Benjamin; Storch, Kirsten; Martz, Kathrin E.; Goettert, Marcia I.; Richters, Andre; Rauh, Daniel; Laufer, Stefan A.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 21 p. 8561 - 8578

4389-50-82-氨基-6-甲基苯甲酸+

77287-34-4甲亚胺酸

75844-41-65-甲基喹唑啉-4(1H)-酮

参考文献

Kulkarni, Shridhar S.; Singh, Satyakam; Shah, Janki R.; Low, Woon-Kai; Talele, Tanaji T.
European Journal of Medicinal Chemistry, 2012 , vol. 50, p. 264 - 273

4389-50-82-氨基-6-甲基苯甲酸

567-61-32-羟基-6-甲基苯甲酸

参考文献

Baur, Benjamin; Storch, Kirsten; Martz, Kathrin E.; Goettert, Marcia I.; Richters, Andre; Rauh, Daniel; Laufer, Stefan A.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 21 p. 8561 - 8578

4389-50-82-氨基-6-甲基苯甲酸

32849-41-58-甲基萘-1-醇

参考文献

Mayer, Patrice; Alibert, Sonia; Brunel, Pascale; Imbert, Thierry
Heterocycles, 2001 , vol. 55, # 2 p. 387 - 392

4389-50-82-氨基-6-甲基苯甲酸+

108-24-7乙酸酐

147006-56-22,5-二甲基-4(3H)-喹唑啉酮

参考文献

Kulkarni, Shridhar S.; Singh, Satyakam; Shah, Janki R.; Low, Woon-Kai; Talele, Tanaji T.
European Journal of Medicinal Chemistry, 2012 , vol. 50, p. 264 - 273

4389-50-82-氨基-6-甲基苯甲酸

17839-53-1

参考文献

Guise, Bruce G.; Ollis, David W.; Peacock, Judith A.; Stephanatou, Julia Stephanidou; Stoddart, Fraser J.
Tetrahedron Letters, 1980 , vol. 21, p. 4203 - 4206

4389-50-82-氨基-6-甲基苯甲酸+

140-89-6乙基黄原酸钾

17839-53-1

参考文献

Gen. Aniline Works
Patent: US1762270 , 1928 ;