6-溴-1-苯并呋喃-2-甲酸合成路线 (共 2 条)
反应条件
1: With tetra-(n-butyl)ammonium iodide; potassium carbonate T=130°C; 4 h; 2: With potassium hydroxide in tetrahydrofuran; water T=0 - 20°C;
参考文献
WO2003/104227 A1, ;
Page 42, 43 ;
反应条件
trifluoroacetic acid in dichloromethane T=0°C; 3 h; Inert atmosphere;
参考文献
ChemMedChem, , vol. 5, # 1 p. 65 - 78