1-苯基-2-丙烯-1-醇合成路线 （共 252 条）
反应条件
bis(η3-allyl-μ-chloropalladium(II)); formic acid methyl ester; polyoxyethanyl-α-tocopheryl sebacate; potassium carbonate; bis-diphenylphosphine in water T=20°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Organic Letters, , vol. 11, # 11 p. 2377 - 2379
反应条件
1: 3-phenyl-3-hydroxypropene With α-cyclohexylcyclohexanemethanamine; tetrabutylammomium bromide in N,N-dimethyl acetamide; water T=20°C; Heck reaction; 0.25 h; 2: 2-iodophenol With 4'-hydroxyacetophenone oxime palladacycle catalyst in N,N-dimethyl acetamide; water T=120°C; Heck reaction; 4 h; Further stages. Title compound not separated from byproducts.;
参考文献
Alacid, Emilio; Najera, Carmen
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2572 - 2584
反应条件
1: 3-phenyl-3-hydroxypropene With α-cyclohexylcyclohexanemethanamine; tetrabutylammomium bromide in water T=20°C; Heck reaction; 0.25 h; 2: 2-iodophenol With 4'-hydroxyacetophenone oxime palladacycle catalyst in water T=120°C; Heck reaction; 14 h; Further stages. Further byproducts. Title compound not separated from byproducts.;
参考文献
Alacid, Emilio; Najera, Carmen
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2572 - 2584
反应条件
1: 3-phenyl-3-hydroxypropene With α-cyclohexylcyclohexanemethanamine; tetrabutylammomium bromide in N,N-dimethyl acetamide T=20°C; Heck reaction; 0.25 h; 2: ortho-bromo-phenol With 4'-hydroxyacetophenone oxime palladacycle catalyst in N,N-dimethyl acetamide T=120°C; Heck reaction; 14 h; Further stages.;
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 17-18 p. 2572 - 2584
参考文献
Rupe; Mueller
Helvetica Chimica Acta, 1921 , vol. 4, p. 847
反应条件
[Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2; 4-hydroxybutanol; N-[(1S,2S)-2-amino-1,2-diphenylethyl]-p-tolylsulphonamide; potassium hydroxide T=110°C; 72 h; optical yield given as percent ee;
参考文献
Chemistry - An Asian Journal, , vol. 5, # 3 p. 538 - 542
参考文献
Rupe; Mueller
Helvetica Chimica Acta, 1921 , vol. 4, p. 847
反应条件
N-chloro-succinimide; [{Cp*IrCl2}]2 in tetrahydrofuran; water T=20°C; 20 h;
参考文献
Ahlsten, Nanna; Gomez, Antonio Bermejo; Martin-Matute, Belen
Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6273 - 6276
Angew. Chem., 2013 , vol. 125, # 24 p. 6393 - 6396,4
反应条件
1: 3-phenyl-3-hydroxypropene With α-cyclohexylcyclohexanemethanamine in water T=20°C; Heck reaction; 0.25 h; 2: iodobenzene With Kaiser oxime-derived complex on resin base in water T=120°C; Heck reaction; 16 h; Further stages. Title compound not separated from byproducts.;
参考文献
Alacid, Emilio; Najera, Carmen
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2572 - 2584
反应条件
hydrogenchloride; diethyl ether
参考文献
Justus Liebigs Annalen der Chemie, , vol. 475, p. 178
