1-苯基-2-丙烯-1-醇合成路线 （共 252 条）
参考文献
Klages
Chemische Berichte, 1906 , vol. 39, p. 2589
反应条件
1: 3-phenyl-3-hydroxypropene With α-cyclohexylcyclohexanemethanamine in water
T=20°C; Heck reaction; 0.25 h;
2: iodobenzene With 4'-hydroxyacetophenone oxime palladacycle catalyst in water
T=120°C; Heck reaction; 10 h; Further stages.;
参考文献
Alacid, Emilio; Najera, Carmen
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2572 - 2584
反应条件
1: 3-phenyl-3-hydroxypropene With α-cyclohexylcyclohexanemethanamine in water
T=20°C; Heck reaction; 0.25 h;
2: iodobenzene With Kaiser oxime-derived complex on resin base in water
T=120°C; Heck reaction; 16 h; Further stages. Title compound not separated from byproducts.;
参考文献
Alacid, Emilio; Najera, Carmen
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2572 - 2584
反应条件
[Pd(acetonitrile)4][BF4]2 in dimethylsulfoxide-d6; methanol-d4
T=50°C; 15 h;
参考文献
Larsson, Johanna M.; Szabo, Kalman J.
Journal of the American Chemical Society, 2013 , vol. 135, # 1 p. 443 - 455
反应条件
1: 3-phenyl-3-hydroxypropene With [Pd(acetonitrile)4][BF4]2 in dimethylsulfoxide-d6; methanol-d4
T=50°C; 15 h;
2: hexamethyl-silane With [Pd(acetonitrile)4][BF4]2 in dimethylsulfoxide-d6; methanol-d4
T=50°C; 15 h;
参考文献
Larsson, Johanna M.; Szabo, Kalman J.
Journal of the American Chemical Society, 2013 , vol. 135, # 1 p. 443 - 455
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; boron trifluoride diethyl etherate in dimethylsulfoxide-d6
T=50°C; 15 h;
参考文献
Larsson, Johanna M.; Szabo, Kalman J.
Journal of the American Chemical Society, 2013 , vol. 135, # 1 p. 443 - 455
反应条件
1: [Pd(acetonitrile)4][BF4]2 / dimethyl sulfoxide / 15 h / 50 °C
2: [Pd(acetonitrile)4][BF4]2 / dimethylsulfoxide-d6; methanol-d4 / 1 h / 50 °C
View Scheme
参考文献
Larsson, Johanna M.; Szabo, Kalman J.
Journal of the American Chemical Society, 2013 , vol. 135, # 1 p. 443 - 455
反应条件
1: [Pd(acetonitrile)4][BF4]2 / dimethyl sulfoxide / 15 h / 50 °C
2: [Pd(acetonitrile)4][BF4]2 / dimethylsulfoxide-d6; methanol-d4 / 15 h / 50 °C
View Scheme
参考文献
Larsson, Johanna M.; Szabo, Kalman J.
Journal of the American Chemical Society, 2013 , vol. 135, # 1 p. 443 - 455
反应条件
oxygen; palladium diacetate in water-d2; acetic acid
Heck Reaction; P=760.051 Torr; Schlenk technique; Mechanism; Reagent/catalystSolventTemperature;
参考文献
Huang, Liangbin; Qi, Ji; Wu, Xia; Wu, Wanqing; Jiang, Huanfeng
Chemistry - A European Journal, 2013 , vol. 19, # 46 p. 15462 - 15466
反应条件
n-butyllithium; 2,2'-dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane; palladium; triphenylphosphine
1.) THF, 0 deg C, 15 min, 2.) reflux, 3 h; Yield given. Multistep reaction;
参考文献
Kumareswaran; Vankar, Yashwant D.
Tetrahedron Letters, 1997 , vol. 38, # 48 p. 8421 - 8424
