1-苯基-2-丙烯-1-醇合成路线 （共 252 条）
反应条件
1: pyridine / tetrahydrofuran / 1 h / 0 °C
2: [(COD)IrCl]2; chiral biphenyl-2,2'-diyl-phosphoramidite / tetrahydrofuran / 1.5 h / 20 °C
View Scheme
参考文献
Shekhar, Shashank; Trantow, Brian; Leitner, Andreas; Hartwig, John F.
Journal of the American Chemical Society, 2006 , vol. 128, # 36 p. 11770 - 11771
反应条件
1: 1.27 g / 4-dimethylaminopyridine; Et3N / 1,2-dichloro-ethane / 80 °C
2: 97 percent / [(1,3-(2,6-i-Pr2Ph)2-1,3-dihydro-2H-imidazol-2-ylidene)AuCl]; AgBF4 / 1,2-dichloro-ethane / 0.2 h / 80 °C / microwave irradiation
View Scheme
参考文献
Marion, Nicolas; Gealageas, Ronan; Nolan, Steven P.
Organic Letters, 2007 , vol. 9, # 14 p. 2653 - 2656
反应条件
toluene-4-sulfonic acid in acetonitrile
Heating;
参考文献
Sanz, Roberto; Martinez, Alberto; Miguel, Delia; Alvarez-Gutierrez, Julia M.; Rodriguez, Felix
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 14 p. 1841 - 1845
反应条件
[Ru(Cp*)(MeCN)2(η3-PhCH=CHCH2)](PF6)2 in acetonitrile
T=79.84°C; 0.0666667 h; Title compound not separated from byproducts.;
参考文献
Nieves, Ignacio Fernandez; Schott, Daniele; Gruber, Stefan; Pregosin, Paul S.
Helvetica Chimica Acta, 2007 , vol. 90, # 2 p. 271 - 276
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) in tetrahydrofuran; water
T=30°C; 15 h; Inert atmosphere; regiospecific reaction;
参考文献
Ahlsten, Nanna; Bartoszewicz, Agnieszka; Agrawal, Santosh; Martin-Matute, Belen
Synthesis, 2011 , # 16 art. no. C57411SS, p. 2600 - 2608
反应条件
1H-imidazole in dichloromethane
4 h; Ambient temperature;
参考文献
Asao, Naoki; Shimada, Takashi; Sudo, Tomoko; Tsukada, Naofumi; Yazawa, Kazuhiko; Gyoung, Young Soo; Uyehara, Tadao; Yamamoto, Yoshinori
Journal of Organic Chemistry, 1997 , vol. 62, # 18 p. 6274 - 6282
反应条件
aluminum isopropoxide
参考文献
Colonge,J.; Brunie,J.-C.
Bulletin de la Societe Chimique de France, 1963 , p. 42 - 46
反应条件
1.1: Et3N; 4-N,N-dimethylaminopyridine / CH2Cl2 / 20 °C
2.1: CuI / tetrahydrofuran / 0.33 h / 0 °C
2.2: tetrahydrofuran / 0 °C
View Scheme
参考文献
Oestreich, Martin; Auer, Gertrud
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 5 p. 637 - 640
反应条件
ruthenium trichloride
参考文献
Ito, Satoru; Matsumoto, Masakatsu
Synthetic Communications, 1982 , vol. 12, # 10 p. 807 - 812
反应条件
sodium acetate; palladium diacetate in acetonitrile
T=60°C; 0.666667 h;
参考文献
Barbero, Margherita; Cadamuro, Silvano; Dughera, Stefano
Synthesis, 2006 , # 20 p. 3443 - 3452
