4-氰基哌啶合成路线

参考文献

Coburn, Craig A.; Maletic, Milana; Soll, Richard; Li, Chunsing; Luo, Yunfu; Qi, Zhiqi
Patent: US2014/5103 A1, 2014 ;
Location in patent: Paragraph 0459; 0460 ;

39546-32-2哌啶-4-甲酰胺

4395-98-64-氰基哌啶

参考文献

Orjales, Aurelio; Mosquera, Ramon; Toledo, Antonio; Pumar, M. Carmen; Garcia, Neftali; Cortizo, Lourdes; Labeaga, Luis; Innerarity, Ana
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5512 - 5532

39546-32-2哌啶-4-甲酰胺

4395-98-64-氰基哌啶

参考文献

Richardson-Merrell Inc.
Patent: US4284636 A1, 1981 ;

91419-48-61-叔丁氧羰基-4-哌啶甲酰胺

4395-98-64-氰基哌啶

参考文献

G.D. SEARLE and CO.
Patent: EP1221441 A2, 2002 ;
Location in patent: Page 185 - 186 ;

4395-98-64-氰基哌啶

362703-35-34-氨基甲基-1-叔丁氧羰基哌啶-4-甲酸甲酯

参考文献

Woo, Hyun Min; Lee, Yun Suk; Roh, Eun Joo; Seo, Seon Hee; Song, Chi Man; Chung, Hye Jin; Pae, Ae Nim; Shin, Kye Jung
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5910 - 5915

4395-98-64-氰基哌啶+

24424-99-5二碳酸二叔丁酯

91419-52-2N-Boc-4-氰基哌啶

参考文献

Giordanetto, Fabrizio; Wallberg, Andreas; Knerr, Laurent; Selmi, Nidhal; Ullah, Victoria; Thorstensson, Fredrik; Lindelo, Asa; Karlsson, Staffan; Nikitidis, Grigorios; Llinas, Antonio; Wang, Qing-Dong; Lindqvist, Anders; Hoegberg, Agot; Lindhardt, Emma; Astrand, Annika; Duker, Goeran
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 119 - 124

4395-98-64-氰基哌啶

91419-52-2N-Boc-4-氰基哌啶

参考文献

Orjales Venero, Aurelio; Toledo Avello, Antonio; Pumar Duran, Carmen
Patent: US2002/38031 A1, 2002 ;
US 20020038031 A1

4395-98-64-氰基哌啶+

1538-75-6三甲基乙酸酐

91419-52-2N-Boc-4-氰基哌啶

参考文献

Cliffe, Ian A.; Todd, Richard S.; White, Alan C.
Synthetic Communications, 1990 , vol. 20, # 12 p. 1757 - 1767

4395-98-64-氰基哌啶+

540-51-22-溴乙醇

21168-73-0

参考文献

TOLERO PHARMACEUTICALS, INC.; XU, Yong; BRENNING, Benjamin, Gary; KULTGEN, Steven, G.; LIU, Xiaohui; SAUNDERS, Michael; HO, Koc-Kan
Patent: WO2013/13188 A1, 2013 ;
Location in patent: Paragraph 00347; 00348 ;
WO 2013/013188 A1

4395-98-64-氰基哌啶

74130-04-43-苄氨基丙酸甲酯

参考文献

Orjales, Aurelio; Mosquera, Ramon; Toledo, Antonio; Pumar, M. Carmen; Garcia, Neftali; Cortizo, Lourdes; Labeaga, Luis; Innerarity, Ana
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5512 - 5532