4-氯-5-乙基-6-甲基噻吩并[2,3-d]嘧啶合成路线 （共 4 条）
反应条件
thionyl chloride in N,N-dimethyl-formamide 1 h; Reflux;
参考文献
US2013/266563 A1, ;
Paragraph 0296 ;
反应条件
1: morpholine; sulfur / ethanol / 60 °C 2: 170 °C 3: triethylamine; trichlorophosphate / 100 °C View Scheme
参考文献
Synthetic Communications, , vol. 41, # 19 p. 2835 - 2851
反应条件
1: sulfur; triethylamine / ethanol / 1 h / |Reflux 2: sulfuric acid / 2.17 h / 90 - 100 °C 3: thionyl chloride / N,N-dimethyl-formamide / 1 h / |Reflux View Scheme
反应条件
1: 170 °C 2: triethylamine; trichlorophosphate / 100 °C View Scheme
参考文献
Synthetic Communications, , vol. 41, # 19 p. 2835 - 2851
