3-苯基丙-2-烯-1-醇合成路线 （共 318 条）
反应条件
1: 3-phenyl-2-propen-1-ol (cinnamyl alcohol) With sodium hydride in N,N-dimethyl-formamide T=0 - 20°C; Inert atmosphere; 2: allyl bromide in N,N-dimethyl-formamide T=20°C; 3 h; Inert atmosphere;
参考文献
Benedetti, Erica; Simonneau, Antoine; Hours, Alexandra; Amouri, Hani; Penoni, Andrea; Palmisano, Giovanni; Malacria, Max; Goddard, Jean-Philippe; Fensterbank, Louis
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1908 - 1912
反应条件
1.1: 70 percent / PBu3 / tetrahydrofuran 2.1: 4 Angstroem molecular sieves; cumene hydroperoxide / vanadyl acetylacetonate / CH2Cl2 / 0.5 h / -10 °C 2.2: 65 percent / Bu3P / CH2Cl2 / 0.08 h / -10 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 9 p. 1315 - 1329
反应条件
hydrogen bromide T=0 - 20°C; 3 h;
参考文献
Singh, Kamaljeet; Staig, Shannon J.; Weaver, Jimmie D.
Journal of the American Chemical Society, 2014 , vol. 136, # 14 p. 5275 - 5278
参考文献
Meisenheimer; Link
Justus Liebigs Annalen der Chemie, 1930 , vol. 479, p. 211,248
参考文献
Gredy
Bulletin de la Societe Chimique de France, 1936 , vol. <5>3, p. 1102
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1936 , vol. 202, p. 322
反应条件
1: Et3N; DMAP / CH2Cl2 / 15 h / 0 °C 2: 73 percent / Pd(DBA)2 / tetrahydrofuran / 12 h / 20 °C 3: 97 percent / Na2EDTA; di(chloromethyl)dioxirane; Bu4NHSO4 / acetonitrile 4: 52 percent / tBuOK / tetrahydrofuran / -78 °C View Scheme
参考文献
Ma, Yuan
Heteroatom Chemistry, 2002 , vol. 13, # 4 p. 310 - 315
反应条件
1: 86 percent / imidazole / CH2Cl2 / 24 h / 20 °C 2: 100 percent Spectr. / H2 / Pd/C / methanol / 24 h / 20 °C / atmospheric pressure View Scheme
参考文献
Ikawa, Takashi; Hattori, Kazuyuki; Sajiki, Hironao; Hirota, Kosaku
Tetrahedron, 2004 , vol. 60, # 32 p. 6901 - 6911
反应条件
1: titanium(IV) isopropylate; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate / N-undecane; dichloromethane / 3.5 h / -20 °C / Molecular sieve 2: sodium bis(2-methoxyethoxy)aluminium dihydride / ethylene glycol dimethyl ether; toluene / 3 h / 0 - 25 °C / Inert atmosphere 3: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 h / 25 °C / Inert atmosphere 4: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 4 h / 25 °C / Inert atmosphere 5: hydrazine hydrate / ethanol / 3 h / Reflux View Scheme
参考文献
Sasikumar; Nikalje, Milind D.
Synthetic Communications, 2012 , vol. 42, # 20 p. 3061 - 3067
反应条件
oxalic acid in water
参考文献
Jurd,L. et al.
Phytochemistry (Elsevier), 1972 , vol. 11, p. 3287 - 3292
反应条件
manganese(IV) oxide; N-bromosuccinmide in dichloromethane 10 h; Sonication; optical yield given as percent destereoselective reaction;
参考文献
Karama, Usama; Al-Othman, Zeid; Al-Majid, Abdullah; Almansour, Abdulrahman
Molecules, 2010 , vol. 15, # 5 p. 3276 - 3280
