3-苯基丙-2-烯-1-醇合成路线 （共 318 条）
反应条件
sodium hydroxide in nitrogen; water; ethyl acetate; toluene
参考文献
Ciba-Geigy Corporation
Patent: US4962196 A1, 1990 ;
反应条件
(i) , (ii) /BRN= 635782/; Multistep reaction;
参考文献
Barltrop,J.A.; Schofield,P.
Journal of the Chemical Society, 1965 , p. 4758 - 4765
反应条件
Ni(PPh3)4 in toluene
T=25°C; regioselective reaction;
参考文献
Jimenez-Aquino, Agustin; Ferrer Flegeau, Emmanuel; Schneider, Uwe; Kobayashi, Shu
Chemical Communications, 2011 , vol. 47, # 33 p. 9456 - 9458
反应条件
diiodo monosilane in chloroform-d1
T=22°C;
参考文献
Keinan, E.; Perez, D.; Sahai, M.; Shvily, R.
Journal of Organic Chemistry, 1990 , vol. 55, # 9 p. 2927 - 2938
反应条件
1: 3-phenyl-2-propen-1-ol (cinnamyl alcohol) With [(1,5-cyclooctadiene)PtCl2]; ammonium hydroxide; bis[2-(diphenylphosphino)phenyl] ether in 1,4-dioxane; methanol
T=100°C; 24 h; Inert atmosphereAutoclave;
2: di-tert-butyl dicarbonate With triethylamine in dichloromethane
T=0 - 20°C; 24 h; Inert atmosphere;
参考文献
Das, Kalpataru; Shibuya, Ryozo; Nakahara, Yasuhito; Germain, Nicolas; Ohshima, Takashi; Mashima, Kazushi
Angewandte Chemie - International Edition, 2012 , vol. 51, # 1 p. 150 - 154
反应条件
1: 46 percent / K2CO3 / CH2Cl2 / Heating
2: Pd(PPh3)4 / tetrahydrofuran; various solvent(s) / 3 h / 65 °C
View Scheme
参考文献
Tsuboyama; Takeda; Torii; Ogura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2357 - 2363
反应条件
n-butyllithium; 2,2'-dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane; palladium; triphenylphosphine
1.) THF, 0 deg C, 15 min, 2.) reflux, 3 h; Yield given. Multistep reaction;
参考文献
Kumareswaran; Vankar, Yashwant D.
Tetrahedron Letters, 1997 , vol. 38, # 48 p. 8421 - 8424
反应条件
[Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2; glycerol; potassium hydroxide
T=100°C; 6 h; Inert atmosphere;
参考文献
Diaz-Alvarez, Alba E.; Crochet, Pascale; Cadierno, Victorio
Catalysis Communications, 2011 , vol. 13, # 1 p. 91 - 96
反应条件
(o-(diphenylphosphino)aniline)Ru(CO)2Cl2; hydrogen; Na[B(3,5-(CF3)2C6H3)4]
T=150°C; P=760.051 Torr; 24 h;
参考文献
Lee, Chun-Chin; Liu, Shiuh-Tzung
Chemical Communications, 2011 , vol. 47, # 24 p. 6981 - 6983
反应条件
1: hexane / 16 h / 20 °C
2: tris(trimethylsilyl)silane; AIBN / benzene / 20 h / 80 °C
3: NaOH; hydrogen peroxide / H2O / 2 h / 20 °C
View Scheme
参考文献
Nishiyama, Hisao; Kitajima, Toshio; Matsumoto, Makoto; Itoh, Kenji
Journal of Organic Chemistry, 1984 , vol. 49, # 12 p. 2298 - 2300
