3-苯基丙-2-烯-1-醇合成路线 （共 318 条）
反应条件
n-butyllithium; triphenylborane; tetrakis(triphenylphosphine) palladium(0); triphenylphosphine
1.) THF, r.t., 5 min; 2.) r.t., 10 min; 3.) THF, reflux, 3 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Stary, Ivo; Stara, Irena G.; Kocovsky, Pavel
Tetrahedron, 1994 , vol. 50, # 2 p. 529 - 538
反应条件
1: 1.) BF3/Et2O, 2.) FeCl3 / 1.) dioxane, RT, 90 min, 2.) dioxane/aq. methanol, RT, 10 min
2: 85 percent / Zn / pyridine / 0.5 h / Ambient temperature
View Scheme
参考文献
Okamoto; Watanabe; Kawada; Goto; Ashida; Oda; Yajima; Imada; Morimoto
Chemical and pharmaceutical bulletin, 1982 , vol. 30, # 8 p. 2797 - 2819
反应条件
phosphoric acid in benzene
T=75 - 80°C; 12 h;
参考文献
Ahluwalia, V. K.; Arora, K. K.; Mukherjee, Keya
Synthesis, 1984 , # 4 p. 346 - 348
反应条件
1: PBr3 / diethyl ether / 3 h / Heating
2: benzene / 4 h / Heating
View Scheme
参考文献
An, Peng; Yu, Zhipeng; Lin, Qing
Organic Letters, 2013 , vol. 15, # 21 p. 5496 - 5499
反应条件
magnesium oxide in various solvent(s)
T=0 - 20°C;
参考文献
Nwoye, Ernest O.; Dudley, Gregory B.
Chemical Communications, 2007 , # 14 p. 1436 - 1437
反应条件
Pd(BF4)2(MeCN)4 in methanol; dimethyl sulfoxide
T=50°C; 15 h; Air; regioselective reaction;
参考文献
Selander, Nicklas; Paasch, Jennifer R.; Szabo, Kalman J.
Journal of the American Chemical Society, 2011 , vol. 133, # 3 p. 409 - 411
反应条件
1: Et3N; DMAP / CH2Cl2 / 15 h / 0 °C
2: 73 percent / Pd(DBA)2 / tetrahydrofuran / 12 h / 20 °C
View Scheme
参考文献
Ma, Yuan
Heteroatom Chemistry, 2002 , vol. 13, # 4 p. 310 - 315
反应条件
potassium hydroxide; cis-[RuCl2(dimethylsulfoxide-S)3(dimethylsulfoxide-O)] in 1,4-dioxane
T=80°C; 24 h;
参考文献
Martinez, Ricardo; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 2006 , vol. 62, # 38 p. 8988 - 9001
反应条件
propylamine; 4 A molecular sieve; di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium in tetrahydrofuran
T=50°C; 24 h; Title compound not separated from byproducts.;
参考文献
Yamashita, Yasuhiro; Gopalarathnam, Apsara; Hartwig, John F.
Journal of the American Chemical Society, 2007 , vol. 129, # 24 p. 7508 - 7509
反应条件
Pt(COD)Cl2; bis[2-(diphenylphosphino)phenyl] ether in 1,4-dioxane
18 h; Heating;
参考文献
Utsunomiya, Masaru; Miyamoto, Yoshiki; Lpposhi, Junji; Ohshima, Takashi; Mashima, Kazushi
Organic Letters, 2007 , vol. 9, # 17 p. 3371 - 3374
