3-苯基丙-2-烯-1-醇合成路线 （共 318 条）
反应条件
1: 100 percent / Ph3P; DIAD / tetrahydrofuran / 1 h / 20 °C
2: 88 percent / mercaptoacetic acid; Et3N / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Kathryn, E. Bell; Knight, David W.; Gravestock, Michael B.
Tetrahedron Letters, 1995 , vol. 36, # 47 p. 8681 - 8684
反应条件
1: 87 percent / Br2 / CH2Cl2
2: 1) NaN3, 2) NaOH / 1) DMSO, 2) DMSO
3: 88 percent / toluene / 80 °C
View Scheme
参考文献
Sakai; Kawabata; Kishimoto; Ema; Utaka
Journal of Organic Chemistry, 1997 , vol. 62, # 15 p. 4906 - 4907
反应条件
1: 78 percent / pyridine / CH2Cl2 / 3 h / 0 - 20 °C
2: 63 percent / 1,2-bis(diphenylphosphino)ethane / tetrakis(triphenylphosphine)palladium(0) / tetrahydrofuran / 24 h / 20 °C
3: 52 percent / aq. HCl / diethyl ether / 1 h
4: 1.70 g / DMAP; Et3N / CH2Cl2 / 20 °C
5: 75 percent / iodine / acetonitrile / 16 h / 0 - 20 °C
6: 81 percent / DBU / dimethylformamide / 1 h / 90 °C
View Scheme
参考文献
Knight; Redfern; Gilmore
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 21 p. 2874 - 2883
反应条件
in formic acid; water; acetic acid
参考文献
The United States of America as represented by the Secretary of Agriculture
Patent: US3973040 A1, 1976 ;
参考文献
Young et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 293,295
参考文献
Wieland; Kerr
Chemische Berichte, 1930 , vol. 63, p. 570,577
反应条件
sodium hydroxide; potassium perrhuthenate
3 h;
参考文献
Green, Graham; Griffith, William P.; Hollinshead, David M.; Ley, Steven V.; Schroeder, Martin
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 4 p. 681 - 686
反应条件
tert.-butylhydroperoxide; copper(l) chloride in decane; acetonitrile
T=20°C; 5 h;
参考文献
Mannam, Sreedevi; Sekar
Tetrahedron Letters, 2008 , vol. 49, # 15 p. 2457 - 2460
反应条件
potassium permanganate; copper(II) sulfate in dichloromethane
Oxidation; ultrasonic irradiation; KineticsProduct distribution; Further Variations:ultrasound effect;
参考文献
Meciarova, Maria; Toma, Stefan; Heribanova, Andrea
Tetrahedron, 2000 , vol. 56, # 43 p. 8561 - 8566
参考文献
Young et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 293,295
