2-(2-氯-4-甲氧基苯基)-3-氧代丁腈合成路线 （共 2 条）
反应条件
1: With sodium t-butanolate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether 10.5 h; Heating / reflux; 2: in ethylene glycol dimethyl ether; toluene T=20 - 30°C; 1 h; Product distribution / selectivity;
参考文献
ONO PHARMACEUTICAL CO., LTD.
Patent: EP1637531 A1, 2006 ;
Location in patent: Page/Page column 14; 15 ;
反应条件
sodium Condensation; Heating;
参考文献
Saito, Tetsuji; Obitsu, Tetsuo; Kondo, Takashi; Matsui, Toshiaki; Nagao, Yuuki; Kusumi, Kensuke; Matsumura, Naoya; Ueno, Sonoko; Kishi, Akihiro; Katsumata, Seishi; Kagamiishi, Yoshifumi; Nakai, Hisao; Toda, Masaaki
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5432 - 5445
