sulfenylation of the dilithio-derivative;

1: 95 percent / BuLi / tetrahydrofuran / 12 h / 0 °C 2: 90 percent / imidazole / dimethylformamide / 12 h / Ambient temperature View Scheme

1: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature 2: 90 percent / BuLi / diethyl ether / 48 h / 0 °C 3: 90 percent / HOOAc, NaOAc / CH2Cl2 / 3.5 h / 7 °C View Scheme

1: 95 percent / BuLi / tetrahydrofuran / 12 h / 0 °C 2: 90 percent / imidazole / dimethylformamide / 12 h / Ambient temperature 3: 88 percent / BuLi / diethyl ether / 48 h / 0 °C 4: 90 percent / Raney nickel / ethanol / 6 h / Heating 5: 75 percent / HOOAc, NaOAc / CH2Cl2 / 3.5 h / 7 °C View Scheme

1: pyridinium chlorochromate / CH2Cl2 / 40 °C 2: 86 percent 3: H2, 15percent aq. KOH / 5percent Pd/SrCO3 / 3361.5 Torr View Scheme

1: n-BuLi / various solvent(s) / 0 °C 3: 56 percent / H2 / Raney nickel / ethanol / Heating 4: 77 percent / MsCl, LiCl, s-collidine / dimethylformamide View Scheme

1: aq.ammonium hydroxide / Raney nickel / 20 °C / 2585.81 Torr 2: 45 percent / CH2Cl2 View Scheme

1: 80 percent / CrO3, pyridine / CH2Cl2 / 0.33 h 2: 92 percent / toluensulphonic acid / benzene / 4 h / Heating 3: 1.) LDA / 1.) THF, -78 deg C, 10 min, 2.) -78 deg C -> -22 deg C, 2 h 4: 99 percent / pyridine / 40 h / 6 °C 5: chloramine-T / tetrahydrofuran / 1 h 6: 2,6-di-tert-butylpyridine, NaI / acetone / 17.5 h / 54 °C 7: 1.) LDA / 1.) DME, -78 deg C, 12 min, 2.) -78 deg C, 2 h 8: 1.) LDA / 1.) DME, -78 deg C, 10 min, 2.) -78 deg C -> 0 deg C, 25 min 9: 1.) m-CPBA, 2.) pyridine, 3.) Me2S, 4.) PhSH, NEt3 10: 88 percent / AcOH / tetrahydrofuran; H2O / 7 h / 21 °C View Scheme