1: [(1-phenylethyl)sulfonyl]benzene With n-butyllithium in tetrahydrofuran; hexane T=0°C; Inert atmosphere; 2: C4H6Cl2Mg in tetrahydrofuran; hexane T=-78 - -20°C; Inert atmosphere;

1: diethyl ether 2: aqueous H2SO4 View Scheme

sulfuric acid

hydrogenchloride

1: With Oxonereg;; glucose derived ketone; potassium carbonate in ethylene glycol dimethyl ether; acetate buffer T=-10°C; pH=9.3; 8 h; 2: With diethylaluminium chloride in hexane; toluene T=-78°C; 0.25 h; Title compound not separated from byproducts;

N-iodo-succinimide; water in acetonitrile T=20°C; Inert atmosphere;