吡啶 4-(4-甲基苯基)-合成路线 （共 36 条）
反应条件
C39H32OP2*CuCl; sodium t-butanolate in toluene
T=80°C; Suzuki-Miyaura Coupling; 15 h; Inert atmosphereGlovebox;
参考文献
Zhou, Yiqing; You, Wei; Smith, Kevin B.; Brown, M. Kevin
Angewandte Chemie - International Edition, 2014 , vol. 53, # 13 p. 3475 - 3479
Angew. Chem., 2014 , vol. 126, # 13 p. 3543 - 3547,5
反应条件
copper(I) oxide; N,N-bis-(diphenylphosphanylmethyl)-2-aminopyridine; potassium carbonate; palladium dichloride in ethylene glycol dimethyl ether; N,N-dimethyl acetamide; dimethyl sulfoxide
T=130°C; 24 h; Sealed tubeInert atmosphereMolecular sieveSchlenk technique;
参考文献
He, Run-Tian; Wang, Jian-Feng; Wang, Hui-Fang; Ren, Zhi-Gang; Lang, Jian-Ping
Dalton Transactions, 2014 , vol. 43, # 25 p. 9786 - 9794
反应条件
CH5N*H4O4S; methylamine in water
T=230°C; 60 h;
参考文献
Gromov; Kurchavov
Russian Chemical Bulletin, 2003 , vol. 52, # 7 p. 1606 - 1609
反应条件
potassium permanganate in acetone
T=0°C;
参考文献
Wimalasena, D. Shyamali; Perera, Rohan P.; Heyen, Bruce J.; Balasooriya, Inoka S.; Wimalasena, Kandatege
Journal of Medicinal Chemistry, 2008 , vol. 51, # 4 p. 760 - 768
反应条件
C52H44CoN4O4; potassium hydroxide; tert-butyl alcohol
T=200°C; 10 h; Inert atmosphereDarkness;
参考文献
Qian, Ying Ying; Wong, Ka Lai; Zhang, Meng Wen; Kwok, Tsz Yiu; To, Ching Tat; Chan, Kin Shing
Tetrahedron Letters, 2012 , vol. 53, # 13 p. 1571 - 1575
反应条件
[PdCl{[(η5-C5H5)]Fe[(η5-C5H3)-N2C4H2-Cl]}(DCPAB)]; potassium tert-butylate
T=120°C; Suzuki coupling; 12 h;
参考文献
Xu, Chen; Duan, Lu-Meng; Li, Zhen; Lou, Xin-Hua; Wang, Zhi-Qiang; Fan, Yao-Ting
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 4 p. 1383 - 1385
反应条件
manganese(IV) oxide in toluene
3 h; Heating;
参考文献
Soldatenkov; Polyanskii; Temesgen; Sergeeva; Vysotskaya; Averkiev; Antipin; Lobanov
Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 5 p. 641 - 649
反应条件
palladium aluminium oxide; nitrobenzene
T=160°C;
参考文献
Schmidle et al.
Journal of Organic Chemistry, 1956 , vol. 21, p. 1195
反应条件
1: 1-methyl-4-(methylethenyl)benzene With ammonium chloride
T=80°C; 7 h;
2: formaldehyd With hydrogenchloride; manganese(IV) oxide
T=80°C; 7 h;
参考文献
Soldatenkov; Polyanskii; Temesgen; Soldatova; Sergeeva; Kolyadina; Lobanov
Mendeleev Communications, 2001 , vol. 11, # 4 p. 154 - 155
反应条件
dipotassium peroxodisulfate; silver nitrate; trifluoroacetic acid in dichloromethane; water
T=23°C; 3 h;
参考文献
Seiple, Ian B.; Su, Shun; Rodriguez, Rodrigo A.; Gianatassio, Ryan; Fujiwara, Yuta; Sobel, Adam L.; Baran, Phil S.
Journal of the American Chemical Society, 2010 , vol. 132, # 38 p. 13194 - 13196
