1,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮合成路线

参考文献

Beckwith,A.L.J.; Gara,W.B.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1975 , p. 593 - 600

4424-80-01,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮+

64-17-5乙醇

145486-67-54-(2-氨基苯基)丁酸

参考文献

v. Braun; Bartsch
Chemische Berichte, 1912 , vol. 45, p. 3388

4424-80-01,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮

22245-92-77-氨基-1,3,4,5-四氢-苯并[B]氮杂革-2-酮

参考文献

Weinberg, Linda R.; Albom, Mark S.; Angeles, Thelma S.; Husten, Jean; Lisko, Joseph G.; McHugh, Robert J.; Milkiewicz, Karen L.; Murthy, Seetha; Ott, Gregory R.; Theroff, Jay P.; Tripathy, Rabindranath; Underiner, Ted L.; Zificsak, Craig A.; Dorsey, Bruce D.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 164 - 167

4424-80-01,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮

19652-38-1

参考文献

Tomasi, Sophie; Renault, Jacques; Martin, Benedicte; Duhieu, Stephane; Cerec, Virginie; Le Roch, Myriam; Uriac, Philippe; Delcros, Jean-Guy
Journal of Medicinal Chemistry, 2010 , vol. 53, # 21 p. 7647 - 7663

4424-80-01,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮+

507-09-5硫代乙酸

19652-38-1

参考文献

Behringer; Meier
Justus Liebigs Annalen der Chemie, 1957 , vol. 607, p. 67,76

4424-80-01,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮

22344-77-07-氯-4,5-二氢-1H-苯并[b]氮杂革-2(3H)-酮

参考文献

Chen; Gilman
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 3 p. 663 - 666

4424-80-01,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮

20678-82-41,3,4,5-四氢-1-甲基-2H-1-苯并氮杂卓-2-酮

参考文献

Zeneca Limited; Zeneca Pharma S.A.
Patent: US5478842 A1, 1995 ;
US 5478842 A

4424-80-01,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮+

74-88-4甲基碘

20678-82-41,3,4,5-四氢-1-甲基-2H-1-苯并氮杂卓-2-酮

参考文献

Takahata; Tomiguchi; Hagiwara; Yamazaki
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 11 p. 3959 - 3964

4424-80-01,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮

22246-45-37-硝基-1,3,4,5-四氢-苯并[B]氮杂革-2-酮

参考文献

Tomasi, Sophie; Renault, Jacques; Martin, Benedicte; Duhieu, Stephane; Cerec, Virginie; Le Roch, Myriam; Uriac, Philippe; Delcros, Jean-Guy
Journal of Medicinal Chemistry, 2010 , vol. 53, # 21 p. 7647 - 7663

4424-80-01,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮

22246-45-37-硝基-1,3,4,5-四氢-苯并[B]氮杂革-2-酮

参考文献

Johnson, Paul D.; Aristoff, Paul A.; Zurenko, Gary E.; Schaadt, Ronda D.; Yagi, Betty H.; Ford, Charles W.; Hamel, Judith C.; Stapert, Douglas; Moerman, Judy K.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 23 p. 4197 - 4200