4-(4-甲烷磺酰基-哌嗪-1-基)-苯胺合成路线 （共 5 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=20°C;
参考文献
WO2012/59932 A1, ;
Page/Page column 118-119 ;
WO 2012/059932 A1
反应条件
triethylamine in dichloromethane
参考文献
US2004/87575 A1, ;
US 20040087575 A1
反应条件
1: triethylamine / dichloromethane / 1 h / 0 - 5 °C 2: hydrogen / palladium 10 on activated carbon / methanol / 20 °C View Scheme
参考文献
WO2012/59932 A1, ;
WO 2012/059932 A1
反应条件
1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C 2: triethylamine / dichloromethane / 1 h / 0 - 5 °C 3: hydrogen / palladium 10 on activated carbon / methanol / 20 °C View Scheme
参考文献
WO2012/59932 A1, ;
WO 2012/059932 A1
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 80 °C 2: trifluoroacetic acid / dichloromethane / 1 h / 20 °C 3: triethylamine / dichloromethane / 1 h / 0 - 5 °C 4: hydrogen / palladium 10 on activated carbon / methanol / 20 °C View Scheme
参考文献
WO2012/59932 A1, ;
WO 2012/059932 A1
