反应条件
1.1: 56 mg / imidazole / CH2Cl2 / 11 h / 20 °C
2.1: 91 percent / tetrahydrofuran; various solvent(s) / -78 - -40 °C
3.1: 99 percent / DIBAL-H / toluene; various solvent(s) / 0.75 h / -78 °C
4.1: 62 percent / SnCl4 / CH2Cl2; heptane / 1.5 h / -78 °C
5.1: 68 percent / dioxane / 30 h / Heating
6.1: DDQ / methanol; CH2Cl2 / 2 h / 20 °C
6.2: 89 percent / PPTS / CH2Cl2; methanol / 6 h / 45 °C
View Scheme
参考文献
Boeckman Jr., Robert K.; Clark, Tammy J.; Shook, Brian C.
Organic Letters, 2002 , vol. 4, # 12 p. 2109 - 2112
