6,7,12,13-四氢-(5,14:8,11)-二乙桥苯并环十二烷合成路线 （共 10 条）
反应条件
1: With N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane
3 h; Reflux;
2: With potassium tert-butylate in toluene
T=80°C; 5 h;
参考文献
Ramm, Sonja Margaretha; Hopf, Henning; Jones, Peter G.; Bubenitschek, Peter; Ahrens, Birte; Ernst, Ludger
European Journal of Organic Chemistry, 2008 , # 17 p. 2948 - 2959
反应条件
tris-(dimethylamino)-phosphine in tetrahydrofuran
Ambient temperatureIrradiation;
参考文献
Higuchi, Hiroyuki; Tani, Keita; Otsubo, Tetsuo; Sakata, Yoshiteru; Misumi, Soichi
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 11 p. 4027 - 4036
参考文献
Cram,D.J. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 1088 - 1093
反应条件
1: (i) AlCl3, CH2Cl2, (ii) /BRN= 1910888/
2: (i) Zn, HCl, (ii) HF
3: Zn, HgCl2, aq. HCl / toluene; ethanol
4: chloranil / xylene
View Scheme
参考文献
Cram,D.J. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 1088 - 1093
反应条件
1: Zn, HgCl2, aq. HCl / toluene; ethanol
2: chloranil / xylene
View Scheme
参考文献
Cram,D.J. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 1088 - 1093
反应条件
1: (i) Zn, HCl, (ii) HF
2: Zn, HgCl2, aq. HCl / toluene; ethanol
3: chloranil / xylene
View Scheme
参考文献
Cram,D.J. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 1088 - 1093
反应条件
phosphorous acid trimethyl ester
2.5 h; Irradiation;
参考文献
Haenel, Matthias W.
Chemische Berichte, 1982 , vol. 115, # 4 p. 1425 - 1436
参考文献
Wasserman,H.H.; Keehn,P.M.
Journal of the American Chemical Society, 1972 , vol. 94, # 1 p. 298 - 300
反应条件
1: NaBH4 / ethanol; tetrahydrofuran / 13 h / 40 - 50 °C
2: 78 percent / tris(dimethylamino)phosphine / tetrahydrofuran / Ambient temperature; Irradiation
View Scheme
参考文献
Higuchi, Hiroyuki; Tani, Keita; Otsubo, Tetsuo; Sakata, Yoshiteru; Misumi, Soichi
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 11 p. 4027 - 4036
反应条件
1: 77 percent / N-bromosuccinimide, azobis(isobutyronitrile) / CCl4 / 2 h / Heating; Irradiation
2: 52 percent / KOH / dioxane; aq. ethanol / 48 h / Heating
3: 80 percent / trimethylphosphit / 2.5 h / Irradiation
View Scheme
参考文献
Haenel, Matthias W.
Chemische Berichte, 1982 , vol. 115, # 4 p. 1425 - 1436
