N,N'-双(2-羟乙基)乙二胺合成路线 （共 13 条）
反应条件
aq. HCl; aq. NaOH in ethanol; water
in the dark; addn. of 1 equiv. of Pt-salt to diamine in EtOH, addn. of doubly distilled H2O, pH was adjusted to 7 by adding HCl, stirring at room temp.; ppt. was collected over a period of 20 h by adjusting of pH with NaOH, ppt. was washed with water, dried over P4O10; elem. anal.;
参考文献
Galanski, Markus; Zimmermann, Wolfgang; Berger, Michael; Baumgartner, Christian; Giester, Gerald; Keppler, Bernhard Klaus
European Journal of Inorganic Chemistry, 2002 , # 2 p. 417 - 422
反应条件
potassium metal in 1,4-dioxane; tert-butyl alcohol
T=40°C; 24 h;
参考文献
Kira, Jaromir; Niedzialkowski, Pawel; Ossowski, Tadeusz
Journal of Coordination Chemistry, 2013 , vol. 66, # 1 p. 180 - 190
反应条件
thionyl chloride
T=90°C; 1 h;
参考文献
Ware; Palmer; Wilson; Denny
Journal of Medicinal Chemistry, 1993 , vol. 36, # 13 p. 1839 - 1846
