2-氟-5-(4-甲氧基苯基)吡啶合成路线 （共 12 条）
反应条件
1.1: 100 percent / aq. HCl / dioxane / 24 h / Heating
2.1: LiH / dimethylformamide / 1.5 h / 50 °C
2.2: 68 percent / dimethylformamide / 16 h
3.1: 83 percent / HBr; AcOH / 16 h / Heating
View Scheme
参考文献
McCarthy, Anna R.; Hartmann, Rolf W.; Abell, Andrew D.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 13 p. 3603 - 3607
反应条件
hydrogenchloride in 1,4-dioxane
24 h; Heating;
参考文献
McCarthy, Anna R.; Hartmann, Rolf W.; Abell, Andrew D.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 13 p. 3603 - 3607
