2-(4-(三氟甲基)苯基)噻唑-4,5-二羧酸二乙酯合成路线

参考文献

Guo, Jiasheng; Erickson, Greg A.; Fitzgerald, Russ N.; Matsuoka, Richard T.; Rafferty, Stephen W.; Sharp, Matthew J.; Sickles, Barry R.; Wisowaty, James C.
Journal of Organic Chemistry, 2006 , vol. 71, # 21 p. 8302 - 8305

22179-72-24-氟硫代苄胺+

34034-87-2α-氯代草酰乙酸二乙酯

444615-63-82-(4-(三氟甲基)苯基)噻唑-4,5-二羧酸二乙酯

参考文献

Banker, Pierette; Cadilla, Rodolfo; Lambert lll, Millard Hurst; Rafferty, Stephen William; Sternbach, Daniel David; Sznaidman, Marcos Luis
Patent: US2004/72838 A1, 2004 ;
US 20040072838 A1

444615-63-82-(4-(三氟甲基)苯基)噻唑-4,5-二羧酸二乙酯+

67-56-1甲醇

444615-64-9(2-(4-(三氟甲基)苯基)噻唑-4,5-二基)二甲醇

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/26849 A1, 2004 ;
Location in patent: Page 8; 9 ;

444615-63-82-(4-(三氟甲基)苯基)噻唑-4,5-二羧酸二乙酯

444615-64-9(2-(4-(三氟甲基)苯基)噻唑-4,5-二基)二甲醇

参考文献

Guo, Jiasheng; Erickson, Greg A.; Fitzgerald, Russ N.; Matsuoka, Richard T.; Rafferty, Stephen W.; Sharp, Matthew J.; Sickles, Barry R.; Wisowaty, James C.
Journal of Organic Chemistry, 2006 , vol. 71, # 21 p. 8302 - 8305