ammonium formate; palladium 10 on activated carbon in methanol; water T=25 - 30°C; 6 h;

ammonium formate; palladium 10 on activated carbon in methanol; water T=25 - 30°C; 6 h;

1: acetic acid; sodium nitrite / water / 0.5 h / 35 °C 2: sulfuric acid / N,N-dimethyl-formamide; toluene / 3 h / Reflux 3: palladium 10 on activated carbon; hydrogen / tetrahydrofuran; methanol View Scheme

1: sodium hydride / methanol / 20 °C 2: sodium tetrahydroborate / methanol / 3 h / 20 °C 3: sodium carbonate / N,N-dimethyl-formamide / 3 h / 100 °C / Inert atmosphere View Scheme

sodium hydrogencarbonate in tetrahydrofuran; ethanol T=75°C;