4-(氰基(苯基)甲基)哌嗪-1-羧酸叔丁酯合成路线 (共 1 条)
反应条件
1: benzaldehyde; piperazine-1-carboxylic acid tert-butyl ester With sodium hydrogensulfite in methanol; water
2: potassium cyanide in methanol; water
T=20°C; 24 h;
参考文献
Bristol-Myers Squibb Company
Patent: US2007/78141 A1, 2007 ;
Location in patent: Page/Page column 17 ;