2-氨基-5,6-二氯-3,4-二氢喹唑啉合成路线 （共 4 条）
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in DMF (N,N-dimethyl-formamide); dichloromethane
参考文献
Shire Holdings AG
Patent: US2006/30574 A1, 2006 ;
Location in patent: Page column 7 ;
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane
参考文献
SHIRE HOLDINGS AG; SHIRE PHARMACEUTICALS, INC.
Patent: WO2006/17822 A2, 2006 ;
Location in patent: Page/Page column 21-22 ;
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in DMF (N,N-dimethyl-formamide); dichloromethane
参考文献
Shire Holdings AG
Patent: US2006/30574 A1, 2006 ;
Location in patent: Page column 7 ;
参考文献
Peters, Jens-Uwe; Luebbers, Thomas; Alanine, Alexander; Kolczewski, Sabine; Blasco, Francesca; Steward, Lucinda
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 1 p. 256 - 261
