5’-氟-2’-甲氧基苯乙酮合成路线 (共 17 条)
参考文献
ICI Australia Limited
Patent: US4251546 A1, 1981 ;
反应条件
potassium carbonate in acetone T=20°C;
参考文献
Zhong, Zhenlin; Snowden, Timothy S.; Best, Michael D.; Anslyn, Eric V.
Journal of the American Chemical Society, 2004 , vol. 126, # 11 p. 3488 - 3495
反应条件
accufluorTM in acetonitrile Fluorination; Heating; Title compound not separated from byproducts.;
参考文献
Stavber, Stojan; Jereb, Marjan; Zupan, Marko
Chemical Communications, 2000 , # 14 p. 1323 - 1324
反应条件
1: in tetrahydrofuran 6 h; Reflux; 2: With hydrogenchloride in water T=75°C; 20 h;
参考文献
Bryan, Marian C.; Biswas, Kaustav; Peterkin, Tanya A.N.; Rzasa, Robert M.; Arik, Leyla; Lehto, Sonya G.; Sun, Hong; Hsieh, Feng-Yin; Xu, Cen; Fremeau, Robert T.; Allen, Jennifer R.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 619 - 622
反应条件
carbon disulfide; aluminium trichloride
参考文献
Buu-Hoi et al.
Journal of Organic Chemistry, 1954 , vol. 19, p. 1617,1621
Bulletin de la Societe Chimique de France, 1956 , p. 629,632
反应条件
1: aqueous NaBrO 2: aqueous HBr; acetic acid View Scheme
参考文献
Buu-Hoi et al.
Journal of Organic Chemistry, 1954 , vol. 19, p. 1617,1621
Bulletin de la Societe Chimique de France, 1956 , p. 629,632
反应条件
AlCl3, aluminium chloride in dichloromethane T=-5 - 25°C;
参考文献
Journal of Chemical Research, , # 4 p. 222 - 227
参考文献
Horton,W.J.; Robertson,D.E.
Journal of Organic Chemistry, 1960 , vol. 25, p. 1016 - 1020
反应条件
bromine in diethyl ether T=20°C;
参考文献
Shen, Li; Yang, Xiaochun; Yang, Bo; He, Qiaojun; Hu, Yongzhou
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 1 p. 11 - 18
反应条件
(i) I2, (ii) NH3*H2O; Multistep reaction;
参考文献
Srivastava; Bahel
Journal of the Indian Chemical Society, 1976 , vol. 53, # 8 p. 841 - 845