3-氟-4-(三氟甲基)苯硼酸频那醇酯合成路线 (共 2 条)
反应条件
potassium acetate; bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane T=100°C; 12 h; Inert atmosphere;
参考文献
WO2010/127856 A1, ;
Page/Page column 89 ;
反应条件
Oxonereg; in water; acetone 0.25 h;
参考文献
PFIZER LIMITED; ICAGEN, INC.; MARKWORTH, Christopher John; MARRON, Brian Edward; RAWSON, David James; STORER, Robert Ian; SWAIN, Nigel Alan; WEST, Christopher William; ZHOU, Shulan
Patent: WO2012/4706 A2, 2012 ;
Location in patent: Page/Page column 50 ;
WO 2012/004706 A2