2,4-二氟-1-硝基苯合成路线 （共 113 条）
反应条件
1: 4-chloro-phenol With iron(III) chloride; lithium in ammonia T=-40°C; Metallation; 2: 2,4-difluoro-1-nitro-benzene in ammonia T=-33°C; Substitution; 10 h; Title compound not separated from byproducts;
参考文献
Politanskaya; Malykhin; Shteingarts
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 8 p. 1131 - 1142
反应条件
1: 3-fluoro-phenol With iron(III) chloride; lithium in ammonia T=-40°C; Metallation; 2: 2,4-difluoro-1-nitro-benzene in ammonia T=-33°C; Substitution; 0.25 h; Title compound not separated from byproducts;
参考文献
Politanskaya; Malykhin; Shteingarts
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 8 p. 1131 - 1142
反应条件
1: m-monochlorophenol With iron(III) chloride; lithium in ammonia T=-40°C; Metallation; 2: 2,4-difluoro-1-nitro-benzene in ammonia T=-33°C; Substitution; 0.25 h; Title compound not separated from byproducts;
参考文献
Politanskaya; Malykhin; Shteingarts
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 8 p. 1131 - 1142
反应条件
ammonia T=25°C; Kinetics;
参考文献
Journal of Organic Chemistry, , vol. 76, # 9 p. 3286 - 3295
参考文献
Politanskaya; Malykhin; Shteingarts
Russian Journal of Organic Chemistry, 1997 , vol. 33, # 5 p. 644 - 651
参考文献
Politanskaya; Malykhin; Shteingarts
Russian Journal of Organic Chemistry, 1997 , vol. 33, # 5 p. 644 - 651
参考文献
Politanskaya; Malykhin; Shteingarts
Russian Journal of Organic Chemistry, 1997 , vol. 33, # 5 p. 644 - 651
参考文献
Politanskaya; Malykhin; Shteingarts
Russian Journal of Organic Chemistry, 1997 , vol. 33, # 5 p. 644 - 651
反应条件
in ammonia T=-33°C; various lithium phenoxides under different temperatures; Product distribution;
参考文献
Politanskaya; Malykhin; Shteingarts
Russian Journal of Organic Chemistry, 1997 , vol. 33, # 5 p. 644 - 651
反应条件
1.1: potassium tert-butylate / tetrahydrofuran / 20 °C / Large scale reaction 1.2: 20 °C / Large scale reaction 1.3: 10 °C / pH 4 - 5 / Large scale reaction 2.1: sulfuric acid; acetic acid / 30 - 70 °C / Large scale reaction 3.1: methanol / 30 - 35 °C / Large scale reaction 4.1: sodium dithionite / tetrahydrofuran; water / 20 °C / Large scale reaction 5.1: boron tribromide / dichloromethane / -8 - 0 °C View Scheme
参考文献
Huang, Yun-Sheng; Zhang, Wen-Qing; Zhang, Xu; Wang, Jian-Zhong
Research on Chemical Intermediates, 2010 , vol. 36, # 8 p. 975 - 983
