2-硝基-5-氟苯酚合成路线

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Lim, Kwang Su; Lee, Hobin; Kim, Sung Eun; Ha, Tae-Hwan; Ann, Jihyae; Son, Karam; Choi, Sun; Sun, Wei; Pearce, Larry V.; Deandrea-Lazarus, Ian A.; Blumberg, Peter M.; Lee, Jeewoo
European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 233 - 243

446-36-62-硝基-5-氟苯酚+

100-39-0溴化苄

129464-01-34-氟-1-硝基-2-(苯基甲氧基)苯

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Takeda Pharmaceutical Company Limited
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446-36-62-硝基-5-氟苯酚+

100-39-0溴化苄+

584-08-7碳酸钾

129464-01-34-氟-1-硝基-2-(苯基甲氧基)苯

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E. I. du Pont de Nemours and Company
Patent: US5750471 A1, 1998 ;

446-36-62-硝基-5-氟苯酚+

620-05-3苄基碘

129464-01-34-氟-1-硝基-2-(苯基甲氧基)苯

参考文献

Park, Chi Hoon; Choe, Hyeonjeong; Jang, In-Young; Kwon, So Yeong; Latif, Muhammad; Lee, Heung Kyoung; Lee, Hyeon Ji; Yang, Eun Hye; Yun, Jeong In; Chae, Chong Hak; Cho, Sung Yun; Choi, Sang Un; Ha, Jae Du; Jung, Heejung; Kim, Hyoung Rae; Kim, Pilho; Lee, Chong Ock; Yun, Chang-Soo; Lee, Kwangho
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 22 p. 6192 - 6196

446-36-62-硝基-5-氟苯酚+

56-81-5甘油

135838-04-9

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Shi, Yue-Wen; Shi, Min-Min; Huang, Jia-Chi; Chen, Hong-Zheng; Wang, Mang; Liu, Xiao-Dong; Ma, Yu-Guang; Xu, Hai; Yang, Bing
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446-36-62-硝基-5-氟苯酚

16292-95-83-甲氧基-4-硝基苯酚

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Lim, Kwang Su; Lee, Hobin; Kim, Sung Eun; Ha, Tae-Hwan; Ann, Jihyae; Son, Karam; Choi, Sun; Sun, Wei; Pearce, Larry V.; Deandrea-Lazarus, Ian A.; Blumberg, Peter M.; Lee, Jeewoo
European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 233 - 243

110-91-8吗啉+

446-36-62-硝基-5-氟苯酚

175135-19-05-吗啉酮-2-硝基苯酚

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Wrobel, Zbigniew; Kwast, Andrzej
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1514-87-02-氯-2,2-二氟乙酸甲酯+

446-36-62-硝基-5-氟苯酚

1214329-62-0

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EXELIXIS, INC.; Daiichi Sankyo Company, Limited; NUSS, John; WILLIAMS, Matthew; MOHAN, Raju; MARTIN, Richard; WANG, Tie-lin; TSURUOKA, Hiroyuki; AOKI, Kazumasa; HONZUMI, Masatoshi; ASOH, Yusuke; SAITO, Keiji; HOMMA, Tsuyoshi
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WO 2010/042626 A1

446-36-62-硝基-5-氟苯酚+

1895-39-2二氟氯乙酸钠

1214329-62-0

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SANOFI
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1493-03-4二氟一碘甲烷+

446-36-62-硝基-5-氟苯酚

1214329-62-0

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Park, Chi Hoon; Choe, Hyeonjeong; Jang, In-Young; Kwon, So Yeong; Latif, Muhammad; Lee, Heung Kyoung; Lee, Hyeon Ji; Yang, Eun Hye; Yun, Jeong In; Chae, Chong Hak; Cho, Sung Yun; Choi, Sang Un; Ha, Jae Du; Jung, Heejung; Kim, Hyoung Rae; Kim, Pilho; Lee, Chong Ock; Yun, Chang-Soo; Lee, Kwangho
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 22 p. 6192 - 6196