1-苄基-4-(4-氨基丁基)哌嗪合成路线 （共 2 条）
反应条件
hydrazine hydrate in ethanol
T=80°C; 18 h;
参考文献
GE HEALTHCARE LIMITED; MEDI-PHYSICS, INC.; NEWINGTON, Ian, Martin; WYNN, Duncan George; NAIRNE, Robert James Domett; GUILBERT, Benedicte; MANDAL, Subrata; JINTO, Jose; VARADARAJAN, Sunderaraman; RANGASWAMY, Chitralekha; BETTS, Helen; DAVIS, Rebecca
Patent: WO2011/150183 A1, 2011 ;
Location in patent: Page/Page column 112; 116 ;
WO 2011/150183 A1
反应条件
1: N-ethyl-N,N-diisopropylamine / acetonitrile / 0.5 h / 20 - 130 °C / Microwave irradiation
2: hydrazine hydrate / ethanol / 18 h / 80 °C
View Scheme
参考文献
GE HEALTHCARE LIMITED; MEDI-PHYSICS, INC.; NEWINGTON, Ian, Martin; WYNN, Duncan George; NAIRNE, Robert James Domett; GUILBERT, Benedicte; MANDAL, Subrata; JINTO, Jose; VARADARAJAN, Sunderaraman; RANGASWAMY, Chitralekha; BETTS, Helen; DAVIS, Rebecca
Patent: WO2011/150183 A1, 2011 ;
WO 2011/150183 A1
