3-甲基-1-苯基-2-丁烯合成路线 （共 98 条）
反应条件
[Pd2(dibenzylideneacetone)3]*dibenzylideneacetone in water; N,N-dimethyl-formamide
T=23°C; 2 h;
参考文献
Castano, Ana M.; Echavarren, Antonio M.
Tetrahedron Letters, 1996 , vol. 37, # 36 p. 6587 - 6590
反应条件
bis(dibenzylideneacetone)-palladium(0) in N,N-dimethyl-formamide
T=27°C; 27 h; Mechanism;
参考文献
Valle, L. Del; Stille, J. K.; Hegedus, L. S.
Journal of Organic Chemistry, 1990 , vol. 55, p. 3019 - 3023
反应条件
iron (III) acetylacetonate in tetrahydrofuran
T=25 - 32°C; 2 h;
参考文献
Amano, Takehiro; Ota, Tomomi; Yoshikawa, Kensei; Sano, Tatsuhiko; Ohuchi, Yutaka; et al.
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 5 p. 1656 - 1658
反应条件
1: 4-phenyl-1,3-bis(phenylthio)but-1-ene With Cp2Ti[P(OEt)3]2 in tetrahydrofuran
T=0°C; desulfurization; 0.166667 h;
2: 2-chloro-2-methyl-4-phenylbutane in tetrahydrofuran
Alkylation; 2 h;
参考文献
Takeda, Takeshi; Nozaki, Naoki; Saeki, Naoko; Fujiwara, Tooru
Tetrahedron Letters, 1999 , vol. 40, # 29 p. 5353 - 5356
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate in tetrahydrofuran
T=80°C; Suzuki-Miyaura coupling; 48 h; Inert atmosphere;
参考文献
Gerbino, Dario C.; Mandolesi, Sandra D.; Schmalz, Hans-Guenther; Podesta, Julio C.
European Journal of Organic Chemistry, 2009 , # 23 p. 3964 - 3972
反应条件
1: 4,4,5,5-tetramethyl-2-phenyl-[1,3,2]-dioxaborolane With sec.-butyllithium in tetrahydrofuran; hexane
T=-78 - 20°C; Suzuki-Miyaura coupling; Inert atmosphere;
2: prenyl bromide With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in tetrahydrofuran; hexane
Suzuki-Miyaura coupling; Inert atmosphereReflux;
参考文献
Gerbino, Dario C.; Mandolesi, Sandra D.; Schmalz, Hans-Guenther; Podesta, Julio C.
European Journal of Organic Chemistry, 2009 , # 23 p. 3964 - 3972
反应条件
bei aufeinanderfolgender Destillation ueber Ammoniumjodid und Phosphorpentoxyd im Vakuum;
参考文献
Claisen
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 72
Chemische Berichte, 1925 , vol. 58, p. 279 Anm. 15
反应条件
sodium acetate; sodium iodide; zinc in acetic acid
参考文献
Warrick,P.; Saunders,W.H.
Journal of the American Chemical Society, 1962 , vol. 84, p. 4095 - 4100
反应条件
zinc; nickel dichloride in N,N-dimethyl-formamide
T=100°C; 7 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Goto, Toshio; Onaka, Makoto; Mukaiyama, Teruaki
Chemistry Letters, 1980 , p. 709 - 712
反应条件
2,6-dimethyl-1,4-benzoquinone in dichloromethane
T=20°C; 12 h;
参考文献
Masutani, Kouta; Minowa, Tomofumi; Hagiwara, Yoshiaki; Mukaiyama, Teruaki
Bulletin of the Chemical Society of Japan, 2006 , vol. 79, # 7 p. 1106 - 1117
