2-氟-4-甲基-6-硝基苯胺合成路线 （共 3 条）
反应条件
1: With nitric acid in water
T=0 - 20°C;
2: With potassium hydroxide in methanol
T=20°C; pH=10; 16 h;
参考文献
Lane, Charlotte Alice Louise; Price, David Anthony
Patent: US2006/111416 A1, 2006 ;
Location in patent: Page/Page column 13 ;
US 20060111416 A1
反应条件
1: With nitric acid
T=0°C; 2 h;
2: With potassium hydroxide in methanol
参考文献
O'Neill, Bryan M; Ratto, Jessica E; Good, Kristi L; Tahmassebi, Deborah C; Helquist, Sandra A; Morales, Juan C; Kool, Eric T
The Journal of organic chemistry, 2002 , vol. 67, # 17 p. 5869 - 5875
反应条件
1.1: 94 percent / CHCl3 / 0.67 h
2.1: aq. nitric acid / 2 h / 0 °C
2.2: 1.50 g / potassium hydroxide / methanol
View Scheme
参考文献
O'Neill, Bryan M; Ratto, Jessica E; Good, Kristi L; Tahmassebi, Deborah C; Helquist, Sandra A; Morales, Juan C; Kool, Eric T
The Journal of organic chemistry, 2002 , vol. 67, # 17 p. 5869 - 5875
