2-氨基-4,5,6,7-四氢苯并噻酚-3-羧酸乙酯合成路线 （共 59 条）
参考文献
Santagati, Andrea; Santagati, Maria; Modica, Maria
Heterocycles, 1993 , vol. 36, # 6 p. 1315 - 1321
参考文献
Farmaco, Edizione Scientifica, 1983 , vol. 38, # 10 p. 762 - 774
反应条件
hydrogenchloride in 1,4-dioxane
6 h; Cooling;
参考文献
Jain, Kishor S.; Bariwal, Jitender B.; Phoujdar, Manisha S.; Nagras, Madhuri A.; Amrutkar, Rakesh D.; Munde, Manoj K.; Tamboli, Riyaj S.; Khedkar, Samrat A.; Khiste, Rahul H.; Vidyasagar, Nikhil C.; Dabholkar, Vinit V.; Kathiravan
Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 2 p. 178 - 185
反应条件
in ethanol
5 h; Heating;
参考文献
El-Sherief, Hassan A. H.; El-Naggar, Galal M.; Hozien, Zeinab A.; El-Sawaisi, Suliman M.
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 2 p. 467 - 473
反应条件
in ethanol
0.00555556 h; microwave irradiation;
参考文献
El-Baih, Fatma E. M.; Al-Blowy, Hanan A. S.; Al-Hazimi, Hassan M.
Molecules, 2006 , vol. 11, # 7 p. 498 - 513
反应条件
1: 84.3 percent / zinc / 2 h / Heating
2: 45.45 percent / hydrazine hydrate / methanol / 8 h / Heating
View Scheme
参考文献
Perrissin; Favre; Luu Duc; Huguet; Gaultier; Narcisse
European Journal of Medicinal Chemistry, 1988 , vol. 23, # 5 p. 453 - 456
参考文献
Russo, Filippo; Santagati, Andrea; Santagati, Maria; Caruso, Antonina; Leone, Maria Grazia; et al.
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 91 - 96
反应条件
1: formamide / 6 h / 160 °C / Inert atmosphere
2: trichlorophosphate / 3 h / 90 °C / Inert atmosphere
3: ammonium hydroxide / 1,4-dioxane; water / 1 h / 100 °C / Microwave irradiation
View Scheme
参考文献
Sleebs, Brad E.; Nikolakopoulos, George; Street, Ian P.; Falk, Hendrik; Baell, Jonathan B.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5992 - 5994
反应条件
sodium hydroxide in ethanol
5 h; Heating;
参考文献
Kanwar, Seema; Sharma
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 11 p. 2367 - 2371
反应条件
in ethanol
6 h; Heating;
参考文献
Cannito, A.; Perrissin, M.; Luu-Duc, C.; Huguet, F.; Gaultier, C.; Narcisse, G.
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 8 p. 635 - 639
