Marsilje, Thomas H.; Hedrick, Michael P.; Desharnais, Joel; Tavassoli, Ali; Zhang, Yan; Wilson, Ian A.; Benkovic, Stephen J.; Boger, Dale L.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 20 p. 4487 - 4501
1.1: 43 percent / pyridine / CH2Cl2 / 2 h / 25 °C
2.1: dimethylformamide / 0.75 h / 25 °C
2.2: 57 percent / K2CO3 / dimethylformamide / 18 h
View Scheme
参考文献
Marsilje, Thomas H.; Hedrick, Michael P.; Desharnais, Joel; Tavassoli, Ali; Zhang, Yan; Wilson, Ian A.; Benkovic, Stephen J.; Boger, Dale L.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 20 p. 4487 - 4501
1.1: 43 percent / pyridine / CH2Cl2 / 2 h / 25 °C
2.1: dimethylformamide / 0.75 h / 25 °C
2.2: 57 percent / K2CO3 / dimethylformamide / 18 h
3.1: 63 percent / K2CO3 / dimethylformamide / 1 h / 70 °C
4.1: 52 percent / sodium methoxide / methanol / 1 h / 25 °C
5.1: 39 percent / BBr3 / CH2Cl2 / 1 h / 0 °C
View Scheme
参考文献
Marsilje, Thomas H.; Hedrick, Michael P.; Desharnais, Joel; Tavassoli, Ali; Zhang, Yan; Wilson, Ian A.; Benkovic, Stephen J.; Boger, Dale L.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 20 p. 4487 - 4501
