3,4,5-三甲氧基苯甲酰氯合成路线 （共 203 条）
反应条件
1: dioxane; aqueous NaOH
2: PCl5; acetyl chloride / Behandeln des Reaktionsprodukts mit Dimethylamin
View Scheme
参考文献
Kuehne; Lambert
Journal of the American Chemical Society, 1959 , vol. 81, p. 4278,4283
Organic Syntheses, 1973 , vol. Coll. Vol. V, p. 400
反应条件
in diethyl ether; benzene
5 h; Heating;
参考文献
Voronon, V. G.; Shramova, Z. I.; Aleshina, V. A.; Zaks, A. S.; Pidemskii, E. L.; Goleneva, A. F.
Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 6 p. 396 - 399
Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 6 p. 35 - 39
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine; potassium tert-butylate
1.) deg C; 2.) THF, 0 deg C, 1h; Multistep reaction;
参考文献
Cummings, Richard T.; DiZio, James P.; Krafft, Grant A.
Tetrahedron Letters, 1988 , vol. 29, # 1 p. 69 - 72
反应条件
1: pyridine
2: KOH; pyridine
View Scheme
参考文献
Baker; Glockling
Journal of the Chemical Society, 1950 , p. 2759,2762
反应条件
triethylamine in benzene
T=20°C; 2 h;
参考文献
Vakhatova, G. M.; Prokopov, A. A.; Shvarts, G. Ya.; Syubaev, R. D.; Yakhontov, L. N.
Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 7 p. 491 - 494
Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 7 p. 50 - 55
反应条件
1: pyridine / 1) 0-5 deg C 2) 1h, room temperature
2: 85 percent / pyridine; H2O / 10 h / Heating
View Scheme
参考文献
Husain, M. I.; Srivastava, G. C.; Dua, P. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 4 p. 381 - 383
反应条件
1: pyridine / 1) 0-5 deg C 2) 1h, room temperature
2: 70 percent / pyridine; H2O / 10 h / Heating
View Scheme
参考文献
Husain, M. I.; Srivastava, G. C.; Dua, P. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 4 p. 381 - 383
反应条件
1: pyridine / 1) 0-5 deg C 2) 1h, room temperature
2: 25 percent / pyridine; H2O / 10 h / Heating
View Scheme
参考文献
Husain, M. I.; Srivastava, G. C.; Dua, P. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 4 p. 381 - 383
反应条件
1: pyridine / 1) 0-5 deg C 2) 1h, room temperature
2: 85 percent / pyridine; H2O / 10 h / Heating
3: SOCl2 / benzene / 6 h / Heating
4: 65 percent / benzene / 2 h / Heating
View Scheme
参考文献
Husain, M. I.; Srivastava, G. C.; Dua, P. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 4 p. 381 - 383
反应条件
1: pyridine / 1) 0-5 deg C 2) 1h, room temperature
2: 75 percent / pyridine; H2O / 10 h / Heating
3: SOCl2 / benzene / 6 h / Heating
4: 69 percent / benzene / 2 h / Heating
View Scheme
参考文献
Husain, M. I.; Srivastava, G. C.; Dua, P. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 4 p. 381 - 383
