4-[(2R)-环氧乙烷基甲基]吗啉合成路线 （共 2 条）
反应条件
1: in tert-butyl alcohol
T=0 - 20°C;
2: With potassium tert-butylate in tetrahydrofuran; tert-butyl alcohol
T=10 - 20°C;
参考文献
SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD.
Patent: US2012/295887 A1, 2012 ;
Location in patent: Page/Page column 5-6 ;
反应条件
in water
T=35°C; 1.5 h;
参考文献
Cegla, Marek T.; Potaczek, Joanna; Zylewski, Marek; Strekowski, Lucjan
Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 2 p. 191 - 194
