1-(3,5-二甲基苯基)-4-羟基-1-丁酮合成路线 （共 1 条）
反应条件
1: 1-bromo-3,5-dimethyl-benzene With n-butyllithium in tetrahydrofuran; diethyl ether
T=-78 - -65°C; 1 h; Inert atmosphere;
2: tetrahydrofuran-2-one in tetrahydrofuran; diethyl ether
T=-78°C;
3: With ammonium chloride in tetrahydrofuran; diethyl ether; water
参考文献
Andrews, David M.; Arnould, Jean-Claude; Boutron, Pascal; Delouvrie, Benedicte; Delvare, Christian; Foote, Kevin M.; Hamon, Annie; Harris, Craig S.; Lambert-van der Brempt, Christine; Lamorlette, Maryannick; Matusiak, Zbegniew M.
Tetrahedron, 2009 , vol. 65, # 29-30 p. 5805 - 5816
