1,4-双(三甲硅基)-1,3-丁二炔合成路线 （共 93 条）
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride in tetrahydrofuran; toluene T=50°C;
参考文献
McCormick, Theresa M.; Jahnke, Ashlee A.; Lough, Alan J.; Seferos, Dwight S.
Journal of the American Chemical Society, 2012 , vol. 134, # 7 p. 3542 - 3548
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-benzyl-N,N,N-triethylammonium chloride in sodium hydroxide; benzene
T=40°C; Addition; 48 h;
参考文献
Inoue, Shinobu; Jigami, Tetsuya; Nozoe, Hiroshi; Aso, Yoshio; Ogura, Fumio; Otsubo, Tetsuo
Heterocycles, 2000 , vol. 52, # 1 p. 159 - 170
反应条件
hydroxylamine hydrochloride; sodium acetate in ethanol
120 h; Heating;
参考文献
Birkofer,L.; Richtzenhain,K.
Chemische Berichte, 1979 , vol. 112, p. 2829 - 2836
反应条件
methyllithium; lithium bromide in tetrahydrofuran
3.5 h; Ambient temperature;
参考文献
Fiandanese, Vito; Bottalico, Daniela; Marchese, Giuseppe; Punzi, Angela
Tetrahedron, 2004 , vol. 60, # 50 p. 11421 - 11425
反应条件
in tetrahydrofuran
T=-40 - 20°C;
参考文献
Corriu, Robert J.P.; Guerin, Christian; Henner, Bernard J.L.; Jolivet, Agnes
Journal of Organometallic Chemistry, 1997 , vol. 530, # 1-2 p. 39 - 48
反应条件
n-butyllithium; diisobutylaluminium hydride in ethylene glycol dimethyl ether; hexane
T=25°C; 18 h;
参考文献
Miller, Joseph A.; Zweifel, George
Journal of the American Chemical Society, 1983 , vol. 105, # 5 p. 1383 - 1384
反应条件
Yield givenMultistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Block, Eric; Birringer, Marc; He, Chunhong
Angewandte Chemie - International Edition, 1999 , vol. 38, # 11 p. 1604 - 1607
反应条件
Yield givenMultistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Block, Eric; Birringer, Marc; He, Chunhong
Angewandte Chemie - International Edition, 1999 , vol. 38, # 11 p. 1604 - 1607
反应条件
1: 55 percent / AlCl3 / CH2Cl2 / 3 h / 0 °C
2: 48 percent / PPh3 / CH2Cl2 / 0.5 h / 20 °C
3: 64 percent / n-BuLi / hexane / -78 - -10 °C
View Scheme
参考文献
Eisler, Sara; Chahal, Navjot; McDonald, Robert; Tykwinski, Rik R.
Chemistry - A European Journal, 2003 , vol. 9, # 11 p. 2542 - 2550
反应条件
1: methyllithium; lithium bromide / diethyl ether / 0 - 20 °C / Inert atmosphere
2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / tetrahydrofuran / Inert atmosphere
View Scheme
参考文献
Semba, Kazuhiko; Fujihara, Tetsuaki; Xu, Tinghua; Terao, Jun; Tsuji, Yasushi
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 8 p. 1542 - 1550
