3-溴-5-(4-甲氧基苯基)吡啶合成路线 （共 4 条）
反应条件
sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; water; toluene Suzuki reaction; 18 h; Heating;
参考文献
Jacquemard, Ulrich; Dias, Nathalie; Lansiaux, Amelie; Bailly, Christian; Loge, Cedric; Robert, Jean-Michel; Lozach, Olivier; Meijer, Laurent; Merour, Jean-Yves; Routier, Sylvain
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 9 p. 4932 - 4953
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate in ethylene glycol dimethyl ether T=80°C; Suzuki coupling;
参考文献
Bouillon, Alexandre; Lancelot, Jean-Charles; Collot, Valerie; Bovy, Philippe R.; Rault, Sylvain
Tetrahedron, 2002 , vol. 58, # 17 p. 3323 - 3328
反应条件
potassium phosphate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=65°C; Suzuki coupling;
参考文献
Bouillon, Alexandre; Lancelot, Jean-Charles; Collot, Valerie; Bovy, Philippe R.; Rault, Sylvain
Tetrahedron, 2002 , vol. 58, # 17 p. 3323 - 3328
反应条件
1.1: n-BuLi / diethyl ether / 1 h / -78 °C 1.2: B(Oi-Pr)3 / diethyl ether / -78 - 20 °C 1.3: 75 percent / glacial acetic acid / diethyl ether / 2 h / 20 °C 2.1: Pd(PPh3)4; K3PO4 / dimethylformamide / 65 °C View Scheme
参考文献
Bouillon, Alexandre; Lancelot, Jean-Charles; Collot, Valerie; Bovy, Philippe R.; Rault, Sylvain
Tetrahedron, 2002 , vol. 58, # 17 p. 3323 - 3328
