1-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮合成路线

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

WO2010/71828 A2, ;

Page/Page column 15-16 ;

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

Chen, Guoqing; Adams, Jeffrey; Bemis, Jean; Pietro, Lucian Di; Dominguez, Celia; Elbaum, Daniel; Germain, Julie; Huang, Qi; Kim, Joseph L.; Ouyang, Xiaohu; Patel, Vinod F.; Smith, Leon M.; Tasker, Andrew; Xi, Ning; Xu, Shimin; Yuan, Chester Chenguang; Croghan, Michael; Kim, Tae-Seong
Patent: US2003/195230 A1, 2003 ;

453562-67-9

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

Liu, Pingli; Huang, Liang; Lu, Yuelie; Dilmeghani, Mina; Baum, Jean; Xiang, Tingjian; Adams, Jeff; Tasker, Andrew; Larsen, Rob; Faul, Margaret M.
Tetrahedron Letters, 2007 , vol. 48, # 13 p. 2307 - 2310

75-36-5乙酰氯+

179898-72-73,3-二甲基-6-硝基吲哚

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

AMGEN INC.; KING, Anthony; LARSEN, Robert; LI, Tj; LU, Yuelie
Patent: WO2010/71828 A2, 2010 ;
Location in patent: Page/Page column 14-15 ;

342045-15-2

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

Neumann, Julia J.; Rakshit, Souvik; Droge, Thomas; Glorius, Frank
Angewandte Chemie, International Edition, 2009 , vol. 48, # 37 p. 6892 - 6895
Angewandte Chemie, 2009 , vol. 121, # 37 p. 7024 - 7027

453562-67-9+

56-34-8四乙基氯化铵

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

Chen, Guoqing; Adams, Jeffrey; Bemis, Jean; Pietro, Lucian Di; Dominguez, Celia; Elbaum, Daniel; Germain, Julie; Huang, Qi; Kim, Joseph L.; Ouyang, Xiaohu; Patel, Vinod F.; Smith, Leon M.; Tasker, Andrew; Xi, Ning; Xu, Shimin; Yuan, Chester Chenguang; Croghan, Michael; Kim, Tae-Seong
Patent: US2003/195230 A1, 2003 ;

453562-67-9+

68696-18-4四乙基氯化铵一水合物

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;

144-55-8碳酸氢钠+

75-36-5乙酰氯+

179898-72-73,3-二甲基-6-硝基吲哚

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

Kelly, Michael G.; Janagani, Satyanarayana; Wu, Guoxian; Kincaid, John; Lonergan, David; Fang, YunFeng; Wei, Zhi-Liang
Patent: US2005/277643 A1, 2005 ;

453562-67-9+

68696-18-4四乙基氯化铵一水合物+

3375-31-3醋酸钯

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

Bo, Yunxin Y.; Chakrabarti, Partha P.; Chen, Ning; Doherty, Elizabeth M.; Fotsch, Christopher H.; Han, Nianhe; Kelly, Michael G.; Liu, Qingyian; Norman, Mark Henry; Ognyanov, Vassil I.; Wang, Xianghong; Zhu, Jiawang
Patent: US2003/195201 A1, 2003 ;
US 20030195201 A1

90221-50-4N-(2-溴-5-硝基苯基)乙酰胺

453562-68-01-(2,3-二氢-3,3-二甲基-6-硝基-1H-吲哚-1-基)-乙酮

参考文献

Liu, Pingli; Huang, Liang; Lu, Yuelie; Dilmeghani, Mina; Baum, Jean; Xiang, Tingjian; Adams, Jeff; Tasker, Andrew; Larsen, Rob; Faul, Margaret M.
Tetrahedron Letters, 2007 , vol. 48, # 13 p. 2307 - 2310